Results 31 to 40 of about 20,780 (304)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Toxicity evaluation, toxin screening and its intervention of the jellyfish Phacellophora camtschatica based on a combined transcriptome-proteome analysis

open access: yesEcotoxicology and Environmental Safety, 2022
Background: The application of multi-omics technologies provides a new perspective to solve three main problems including species identification, toxin screening and effective antagonist conformation in the studies of marine toxic jellyfish.
Fengling Yang   +11 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Sergei Yesenin in the Encyclopedic Format. Part 1. From the Complete Works and Chronicles to the Yesenin Encyclopedia [PDF]

open access: yesЛитературный факт
The series of articles are devoted to the scientific project “Yesenin Encyclopedia” carried out at the IWL RAS. It is a collection of information about the life and work of S.A.
Natalia I. Shubnikova-Guseva (Guseva)
doaj   +1 more source

Janet Hyde (1986) - Entry for Encyclopedia of Evolutionary Psychological Science

open access: yes, 2018
Encyclopedia entry for T.K. Shackelford & V.A. Weekes-Shackelford (Eds.) (2019). Encyclopedia of evolutionary psychological science.
Katherine S. Corker
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Encyclopedia of Religions and Society

open access: yesAmerican Journal of Islam and Society, 1999
The Encyclopedia ofReligion and Society can be regarded as the fmt substantial reference work specifically concerned with the sociological study of religion.
Sophie Gilliat-Ray
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Arendt on the State, the Nation and the Separation of Education from Politics

open access: yes, 2017
In this encyclopedia entry, Hannah Arendt's claim that education and politics must be kept apart is considered against the background of a discussion of Arendt's view of the State and its problematic relationship with the ...
Lilja, Peter, Peter Lilja
core   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang   +4 more
wiley   +1 more source

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