Results 171 to 180 of about 943,362 (295)
FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li +16 more
wiley +1 more source
Differentially expressed circular RNA profile in hemorrhagic and ischemic moyamoya disease. [PDF]
Zhao M +5 more
europepmc +1 more source
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv +8 more
wiley +1 more source
Investigation into the antidepressant mechanism of the Guizhi-Baishao herbal pair based on network pharmacology and molecular docking. [PDF]
Wen Q, Hu X, Wang X, Zu F, Zhang N.
europepmc +1 more source
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li +10 more
wiley +1 more source
Network pharmacology insights into the mechanistic basis of Taohe Chengqi Decoction in the treatment of constipation. [PDF]
Yin Y, Xie Y, Tan S, Zhang Y, Xu C.
europepmc +1 more source
Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang +15 more
wiley +1 more source
Identifying Potential Drug Targets for Membranous Nephropathy Through an Analysis of Mendelian Randomization. [PDF]
Saed YA +4 more
europepmc +1 more source

