Results 241 to 250 of about 943,362 (295)

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Limited expression of B-cell maturation antigen in acute myeloid leukemia. [PDF]

J Immunother Cancer
Ran Y, Cheng W, Yi X, Yang S, Zhang W, Xu J.   +5 more
europepmc   +1 more source

The Molecular Interplay Between Helicobacter pylori Infection and Ulcerative Colitis: Unraveling Shared Biomarkers and Pathway Networks. [PDF]

Immun Inflamm Dis
Zhu M, Li X, Huang X, Dong R, Zhang S.
europepmc   +1 more source

Network pharmacological and experimental validation of the mechanism of Chaihu Guizhi Ganjiang decoction regulating T helper cell 17/regulatory T cell balance to improve autoimmune hepatitis. [PDF]

J Tradit Chin Med
Zihao L, Jie G, Jinyun S, Qin Z, Hongyu Z.   +4 more
europepmc   +1 more source

Genetic alterations and aberrant hormonal pathways in thymic epithelial tumors. [PDF]

BMC Cancer
Zhang Y, Lian W, Zuo W, Wang F, Zhang Y, He J, Wang Y, Gao W.   +7 more
europepmc   +1 more source

Integrated multi-omics analysis reveals gut microbiota and metabolic characteristics in coronary heart disease. [PDF]

Front Microbiol
Peng L, Zhang Y, Li X, Hu Z.
europepmc   +1 more source

Identification of VEGFB associated with NKT cells in diabetic foot ulcers: Single-cell analysis and machine learning. [PDF]

Medicine (Baltimore)
Wang W, He Y, You T, Lei M, Chen J.
europepmc   +1 more source

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Women's Studies Encyclopedia

1999
Tierney's highly acclaimedWomen's Studies Encyclopediahas become the standard in the field, but research on women has proceeded rapidly since its publication. Feminist thought has grown and branched out, and women's conditions have changed markedly in some areas.
openaire   +1 more source

Encyclopedia of Postcolonial Studies

2001
The collapse of empires has resulted in a remarkable flourishing of indigenous cultures in former colonies. The end of the colonial era has also witnessed a renaissance of creativity in the postcolonial world as modern writers embrace their heritage. The experience of postcoloniality has also drawn the attention of academics from various disciplines ...
openaire   +1 more source

Encyclopedia of black studies

Choice Reviews Online, 2005
Molefi Asante, Ama Mazama
  +4 more sources