Results 41 to 50 of about 943,362 (295)

Deep Transcriptomic Profiling of M1 Macrophages Lacking Trpc3 [PDF]

open access: yes, 2017
In previous studies using mice with macrophage-specific loss of TRPC3 we found a significant, selective effect of TRPC3 on the biology of M1, or inflammatory macrophages.
Atolagbe, Oluwatomisin T.   +5 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Unity of Diversity: confessional and linguistic tolerance, multiculturalism in the Kazan Khanate – the northernmost outpost of the Islamic world in the XV–XVI centuries

open access: yesАрхеология евразийских степей
The article presents the results of many years of research on the ethnosocial and political history of the Kazan Khanate, the culture of the ruling stratum and the taxable population of this medieval state. Historical sources indicate that in the Khanate,
Bulat L. Кhamidullin
doaj   +1 more source

Travel notes of the first half of the 19th century: Tatars of Kazan province through the eyes of travelers

open access: yesИсторическая этнология, 2018
The genre of travel notes is widely used in literature of Russia in the first half of the nineteenth century. It is a traveler’s report about people, cities and countries whch he had met during the trip.
Gulnara E. Rafikova
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

Islam and “Paganism”: Multilingualism and Multicultura­lism in the Kazan Khanate

open access: yesЗолотоордынское обозрение
The aim of the research was to analyze the level of Islamization and, at the same time, cultural and religious tolerance of the multiethnic and multi-confessional Turkic-Finno-Ugric population of the Kazan Khanate.
Khamidullin B.L.
doaj   +1 more source

Simvastatin Restores Uteroplacental Hemodynamics and Trophoblast Function in Obstetric Antiphospholipid Syndrome in a Placenta‐on‐a‐Chip Model

open access: yesAdvanced Healthcare Materials, EarlyView.
Simvastatin mitigates placental hypoperfusion in OAPS by ameliorating abnormal uteromaternal hemodynamics and enhancing trophoblast invasion via optimized endothelial cell interactions under pathological shear stress, as evidenced by results from a placenta‐on‐a‐chip platform.
Hongli Liu   +10 more
wiley   +1 more source

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types. [PDF]

open access: yes, 2019
Cancer cell lines are a cornerstone of cancer research but previous studies have shown that not all cell lines are equal in their ability to model primary tumors.
Aran, D   +9 more
core   +1 more source

Biomimetic Copper‐Doped Nano‐Aluminum Adjuvant Potentiates Therapy in Chemoresistant Acute Myeloid Leukemia

open access: yesAdvanced Healthcare Materials, EarlyView.
We developed a novel copper‐doped aluminum nano‐adjuvant (CuNA) to overcome cytarabine resistance in acute myeloid leukemia (AML). CuNA effectively sensitizes drug‐resistant AML cells to cytarabine by inducing mitochondrial dysfunction and inhibiting HMGCR/GPX4 to amplify ferroptosis.
Chao He   +10 more
wiley   +1 more source

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