Results 81 to 90 of about 943,362 (295)

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Biographical Sketch of Spencer Fullerton Baird [PDF]

open access: yes, 1996
Spencer Fullerton Baird was born in Reading, Pennsylvania, February 3, 1823. In 1834 he was sent to a Quaker boarding-school kept by Dr. McGraw, at Port Deposit, Maryland, and the year following to the Reading Grammar School. In 1836 he entered Dickinson
Goode, George Brown
core  

The Jericho Oasis Archaeological Park - 2015 Interim Report. Italian-Palestinian cooperation for protection and valorization of archaeological heritage [PDF]

open access: yes, 2015
In April 2015, the Italian Cooperation, Sapienza University of Rome and the Palestinian Ministry of Tourism and Antiquities started the Project “Oasis of Jericho” aimed at the implementation of the Jericho Oasis Archaeological Park (JOAP) by means of ...
Hamdan, Iyad   +3 more
core   +1 more source

Single‐Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re‐Sensitizer Drugs in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu   +6 more
wiley   +1 more source

“I am happy to share with you my recent discovery of Uyghur manuscripts”: S.E. Malov’s letters to Academician V.V. Radlov from Chinese Turkestan (1910–1915)

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки
S.E. Malov was an outstanding teacher of Turkology and a prominent expert on ancient Turkic runic and Uyghur monuments, as well as on the history, language, and culture of Turkic-speaking peoples.
Ramil M. Valeev   +4 more
doaj   +1 more source

The Encyclopedia of Ukraine as an object and a source in scientific researches

open access: yesЕнциклопедичний Вісник України, 2017
The views of various experts on the Encyclopedia of Ukraine have been investigated and the main areas of scientific research are outlined in which this encyclopedia is used in studies or is as a source of cited information.
Mykola Zhelezniak , Oleksandr Ishchenko
doaj   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

open access: yesAdvanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang   +10 more
wiley   +1 more source

Hispanic America in Linguistic and Regional Studies: New Educational Encyclopedia

open access: yesИбероамериканские тетради
Book Review: E.V. Astakhova, Yu.V. Davtyan, E.V. Kriukova. Spanish-speaking countries of Latin America and the Caribbean: national images. History. Culture. Language. Textbook on linguistic and regional studies / Ed. by V. Iovenko.
M. M. Raevskaya
doaj   +1 more source

The International Studies Encyclopedia [PDF]

open access: yes, 2017
Over 400 entriesThe International Studies Encyclopedia, published in association with the International Studies Association (ISA), is the most comprehensive reference work of its kind for the fields of international studies and international relations.
openaire   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

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