Results 31 to 40 of about 41,046 (283)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Encyclopedist who has been ahead of his time (to the 125th anniversary of Yevhen Onatskyi’s birthday)

open access: yesЕнциклопедичний Вісник України, 2019
The article is dedicated to Yevhen D. Onatskyi who is a prominent figure of Ukraine, primarily known as an encyclopedist because of The Small Ukrainian Encyclopedia that is his most famous work. The Small Ukrainian Encyclopedia was complied and published
Serhii Bilokin
doaj   +1 more source

Researching trust in Wikipedia [PDF]

open access: yes, 2011
As the use of collaborative online encyclopedias such as Wikipedia grows, so does the need for research on how users evaluate its credibility. In this paper we compare three experimental approaches to study trust in Wikipedia, namely think aloud, eye ...
Lucassen, Teun, Schraagen, Jan Maarten
core   +2 more sources

How Historical Is Begriffsgeschichte? [PDF]

open access: yes, 2012
This is a preprint (author's original) version of the article published in History of European Ideas 25(1-2):9-14. The final version of the article can be found at http://dx.doi.org/10.1016/S0191-6599(99)00015-7 (login required to access content).
Schmidt, James
core   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Uma obra “universal” e universitária – Breve ensaio sobre a Enciclopédia Brasileira do Instituto Nacional do Livro e os projetos da década de 1950

open access: yesRevista Crítica de Ciências Sociais, 2016
This article discusses conceptual changes in the provisional plans for the Instituto Nacional do Livro Enciclopédia Brasileira in the 1950s. It compares the two most important preliminary plans – the 1937 and 1957 versions – and presents the analysis and
Mariana Rodrigues Tavares
doaj   +1 more source

Facts, Damned Lies and Statistics: A 55 Year Stumbling Block [PDF]

open access: yes, 2012
I have to admit something: when it comes to interpretation, I\u27m making this all up as I go along. I don\u27t have some magical cache of best practices stored up, waiting to deposit them week after week in posts here on the blog.
Rudy, John M.
core   +1 more source

Improving information quality of Wikipedia articles with cooperative principle

open access: yes, 2017
Purpose: The purpose of this paper is to investigate the impact of cooperative principle on the information quality (IQ) by making objects more relevant for consumer needs, in particular case Wikipedia articles for students.
Fidler, Miloš, Lavbič, Dejan
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Process of gender socialization through encyclopedias for girls and for boys [PDF]

open access: yes, 2014
В статье приводятся результаты исследования влияния энциклопедий для мальчиков и девочек на гендерную социализацию подростков. Рассмотрены те гендерные особенности, которые транслируются через энциклопедии.The article presents the results of studies of ...
Batyreva, M. V.   +3 more
core  

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