Results 31 to 40 of about 78,649 (333)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Facts, Damned Lies and Statistics: A 55 Year Stumbling Block [PDF]

open access: yes, 2012
I have to admit something: when it comes to interpretation, I\u27m making this all up as I go along. I don\u27t have some magical cache of best practices stored up, waiting to deposit them week after week in posts here on the blog.
Rudy, John M.
core   +1 more source

How Historical Is Begriffsgeschichte? [PDF]

open access: yes, 2012
This is a preprint (author's original) version of the article published in History of European Ideas 25(1-2):9-14. The final version of the article can be found at http://dx.doi.org/10.1016/S0191-6599(99)00015-7 (login required to access content).
Schmidt, James
core   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Encyclopedist who has been ahead of his time (to the 125th anniversary of Yevhen Onatskyi’s birthday)

open access: yesЕнциклопедичний Вісник України, 2019
The article is dedicated to Yevhen D. Onatskyi who is a prominent figure of Ukraine, primarily known as an encyclopedist because of The Small Ukrainian Encyclopedia that is his most famous work. The Small Ukrainian Encyclopedia was complied and published
Serhii Bilokin
doaj   +1 more source

Researching trust in Wikipedia [PDF]

open access: yes, 2011
As the use of collaborative online encyclopedias such as Wikipedia grows, so does the need for research on how users evaluate its credibility. In this paper we compare three experimental approaches to study trust in Wikipedia, namely think aloud, eye ...
Lucassen, Teun, Schraagen, Jan Maarten
core   +2 more sources

Improving information quality of Wikipedia articles with cooperative principle

open access: yes, 2017
Purpose: The purpose of this paper is to investigate the impact of cooperative principle on the information quality (IQ) by making objects more relevant for consumer needs, in particular case Wikipedia articles for students.
Fidler, Miloš, Lavbič, Dejan
core   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Uma obra “universal” e universitária – Breve ensaio sobre a Enciclopédia Brasileira do Instituto Nacional do Livro e os projetos da década de 1950

open access: yesRevista Crítica de Ciências Sociais, 2016
This article discusses conceptual changes in the provisional plans for the Instituto Nacional do Livro Enciclopédia Brasileira in the 1950s. It compares the two most important preliminary plans – the 1937 and 1957 versions – and presents the analysis and
Mariana Rodrigues Tavares
doaj   +1 more source

Process of gender socialization through encyclopedias for girls and for boys [PDF]

open access: yes, 2014
В статье приводятся результаты исследования влияния энциклопедий для мальчиков и девочек на гендерную социализацию подростков. Рассмотрены те гендерные особенности, которые транслируются через энциклопедии.The article presents the results of studies of ...
Batyreva, M. V.   +3 more
core  

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