Results 51 to 60 of about 611,597 (310)

End-stage kidney disease: The last 12 months

open access: yesAustralian Journal of General Practice, 2021
Chronic kidney disease (CKD) is increasingly prevalent in Australia's ageing population. Over the past decade, there has been growing recognition that dialysis does not benefit every patient with end-stage kidney disease (ESKD). Patients with advanced age, significant comorbidities and poor functional status may not gain a survival benefit with ...
Sarah, So   +3 more
openaire   +3 more sources

End-Stage Kidney Disease and Dialysis in Pregnancy [PDF]

open access: yesAdvances in Chronic Kidney Disease, 2020
End-stage kidney disease is associated with low fertility, with rates of conception in women on dialysis estimated at 1/100th of the general population. However, live birth rates are increasing over time in women on hemodialysis, whereas they remain lower and static in women on peritoneal dialysis.
Andrea L. Oliverio   +1 more
openaire   +2 more sources

Clinical Conditions and History of Illness Among Terminal Chronic Kidney Disease Patients [PDF]

open access: yes, 2019
End-stage renal disease (ESRD) is one of the public health problems in Indonesia. This study aimed to determine the clinical condition of premorbid and the incidence of ESRD. The study design is a case-control.
Adiningrat, A. (Arya)   +2 more
core   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Outcomes associated with acute kidney disease: A systematic review and meta-analysisResearch in context

open access: yesEClinicalMedicine, 2023
Summary: Background: Acute kidney disease (AKD) defines the period after kidney damage and it is a critical period of both repair and fibrotic pathways. However, the outcomes of patients with AKD have not been well-defined.
Ching-Chun Su   +13 more
doaj   +1 more source

Cardiovascular Disease and Chronic Inflammation in End Stage Kidney Disease [PDF]

open access: yes, 2013
Background: Chronic Kidney Disease (CKD) is one of the most severe diseases worldwide. In patients affected by CKD, a progressive destruction of the nephrons is observed not only in structuralbut also in functional level. Atherosclerosis is a progressive
Petros Kolovos, Sofia Zyga
core  

Epidemiology: Spotlight on CKD deaths—increasing mortality worldwide [PDF]

open access: yes, 2015
In the USA, mortality among patients with chronic kidney disease (CKD) and end-stage renal disease has declined over the past two decades. By contrast, new data indicate that the rate of CKD-associated deaths is increasing worldwide.
Kovesdy, CP, Rhee, CM
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Genetic Susceptibility to Chronic Kidney Disease: Links, Risks and Management

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2023
Hanny Sawaf,1 Tariku T Gudura,1 Sylvester Dorobisz,1 Dianne Sandy,2 Xiangling Wang,1 Shane A Bobart2 1Department of Kidney Medicine, Cleveland Clinic, Cleveland, OH, USA; 2Department of Kidney Medicine, Cleveland Clinic Florida, Weston, FL ...
Sawaf H   +5 more
doaj  

Cardiovascular Disease Assessment Prior to Kidney Transplantation

open access: yesMethodist DeBakey Cardiovascular Journal, 2022
Cardiovascular disease is highly prevalent and the leading cause of mortality in patients with chronic kidney disease, end-stage kidney disease, and kidney transplantation.
Angelina R. Edwards, Elise C. Ewing
doaj   +1 more source

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