Results 261 to 270 of about 589,938 (329)

Structural Connectivity Disruption and Structural-Functional Decoupling in Working Memory Networks Across Pre-Dialysis and Maintenance Hemodialysis End-Stage Renal Disease Patients. [PDF]

CNS Neurosci Ther
Xu X, Ma S, Liu S, Luo Z, Zhu Q, Yuan H, Zhu X, Gu W, Li P, Zhang J, Zhang M, Mu J.   +11 more
europepmc   +1 more source

Depression in Patients With End-Stage Renal Disease Presenting to a Tertiary Care Hospital, Hyderabad

Raheela, Bhagwan Das, Zubaida, Meenu Minhas, Abdul Rehman Memon, Abdul Qadir   +5 more
openalex   +2 more sources

The Effect of Convective Dialytic Modalities on Arterial Stiffness in End-Stage Renal Disease Patients

, 2016
Panagiotis I. Georgianos, Evangelia Dounousi, Theodoros Eleftheriadis, Vassilios Liakopoulos   +3 more
openalex   +2 more sources

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Development and validation of a risk-based nomogram for predicting peritoneal dialysis catheter dysfunction in end-stage renal disease patients. [PDF]

Langenbecks Arch Surg
Zhao B, Guo S, Li W, Shang H, Xing Y, Liu J, Hu Y, Wang Y, Fu G.   +8 more
europepmc   +1 more source

SUN-086 MORTALITY IN CHILDREN WITH END STAGE OF RENAL DISEASE: A GUATEMALAN RETROSPECTIVE COHORT STUDY

, 2019
Jorge Morales, L. Almorza, Adrián Aguilar, A. Chocó, Randall Lou‐Meda   +4 more
openalex   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Hypoalbuminemia and Hospitalization Risk in Mexican Patients With End-Stage Renal Disease on Hemodialysis: A Single-Center, Retrospective, Cross-Sectional Study. [PDF]

Cureus
Rojano-Mejía D, Figueroa-García J, Ramírez-Fuentevilla R, Roldan-Valadez E, Martínez-Barro D, Hernández-Rivera JCH, Figueroa-Hernández MF, Contreras-Sánchez SE.   +7 more
europepmc   +1 more source

HiST: Histological Images Reconstruct Tumor Spatial Transcriptomics via MultiScale Fusion Deep Learning

Advanced Science, EarlyView.
HiST, a multiscale deep learning framework, reconstructs spatially resolved gene expression profiles directly from histological images. It accurately identifies tumor regions, captures intratumoral heterogeneity, and predicts patient prognosis and immunotherapy response.
Wei Li, Dong Zhang, Eryu Peng, Shijun Shen, Hamid Alinejad‐Rokny, Yao Liu, Junke Zheng, Cizhong Jiang, Youqiong Ye   +8 more
wiley   +1 more source