Results 101 to 110 of about 996,709 (262)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

OPTIMAL ANALYSIS OF THE SHOULDER END STRUCTURE OF SPRING CLIP-Ⅲ FASTENINGS IN METRO LINES

Jixie qiangdu, 2016
Based on the nonlinear contact theory,a finite element model of spring clip-III fastening system used in metro lines is established. The relation between fastening’s clamping force and vertical displacement of its finger is obtained.
ZHANG ShuFeng, WEN ZeFeng, SHANG HongXia, JIN XueSong   +3 more
doaj  

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Phosphorylation Increases Persistence Length and End-to-End Distance of a Segment of Tau Protein. [PDF]

Biophys J, 2016
Chin AF, Toptygin D, Elam WA, Schrank TP, Hilser VJ.   +4 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Algorithm of route discovery based on distance prediction in MANET

Tongxin xuebao, 2010
A scheme of route discovery was provided based on the distance prediction to destination.Hops table was established to store historical records.The long-range information and instantaneous information were extracted from historical records.The distance ...
LI Shi-bao, HONG Li
doaj   +2 more sources

Mining methods of steep end-slope under the influence of internal dump boundaries

矿业科学学报
: In open-pit mining, technological and safety requirements often result in relatively shallow slopes at the end walls, leaving substantial coal resourcesburied and unutilized.The partitioned mining with internal dumping, however, shortens the exposure ...
MA Li, LI Mengbo, BI Yinli, PENG Suping, LI Yinda, ZHAO Xulong, CHANG Zhiguo, YU Chunyu   +7 more
doaj   +1 more source

Trace-distance based end-to-end entanglement fidelity with information preservation in quantum networks

Journal of Network and Computer Applications
Quantum networks hold the potential to revolutionize a variety of fields by surpassing the capabilities of their classical counterparts. Many of these applications necessitate the sharing of high-fidelity entangled pairs among communicating parties.
Pankaj Kumar, Binayak Kar, Shan-Hsiang Shen   +2 more
openaire   +2 more sources