Results 101 to 110 of about 1,979,462 (303)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Swimming velocity, rotational frequency, torsion, and end-to-end distance for varying flagellar attachment.

, 2015
(a) Rescaled swimming velocity plotted versus the winding angle of the helically attached flagellum. The snapshots show the model trypanosomes before applying the bending wave. The flagellum winds counter-clockwise around the cell body up to the angle .
Markus Engstler (120018), Holger Stark (4694), Davod Alizadehrad (682295), Timothy Krüger (120005)   +3 more
core   +1 more source

Adapting Transformer to End-to-End Spoken Language Translation [PDF]

, 2019
Neural end-to-end architectures for sequence-to-sequence learning represent the state of the art in machine translation (MT) and speech recognition (ASR).
Marco Turchi, Matteo Negri, Mattia A. Di Gangi   +2 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Tangentially active polymers in cylindrical channels

SciPost Physics
We present an analytical and computational study characterizing the structural and dynamical properties of an active filament confined in cylindrical channels. We first outline the effects of the interplay between confinement and polar self-propulsion on
José Martín-Roca, Emanuele Locatelli, Valentino Bianco, Paolo Malgaretti, Chantal Valeriani
doaj   +1 more source

Mean end-to-end distance () of the HT5 surfactants, for all persistence length values and surfactant concentrations modeled here.

Mean end-to-end distance () of the HT5 surfactants, for all persistence length values and surfactant concentrations modeled here.
A. Gama Goicochea (17896410), J.D. Hernández Velázquez (17896407)   +1 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Dipole Moment and End-to-End Distance of Syndiotactic Vinyl Polymer [PDF]

Journal of the Physical Society of Japan, 1964
Conformation of the syndiotactic vinyl polymer in dilute solution is treated, and the mean square dipole moment and the mean square end-to distance of the polymer are calculated. The polymer is regarded as a flexible chain made of segments, and the potential of internal rotation of the polymer molecule is approximated by a square well potential ...
openaire   +1 more source

Modification of a specific tyrosine enables tracing of the end-to-end distance during apomyoglobin folding

, 1995
In order to follow the overall geometry of the apomyoglobin molecule during folding, we have converted a specific tyrosine residue into 3-nitro-tyrosine. The specificity of the modification was verified by proteolytic cleavage of the modified protein and
Poulsen, Flemming M., Christian Rischel, Rischel, Christian, Flemming M. Poulsen   +3 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source