Results 91 to 100 of about 364,848 (300)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Remote hearing aid fitting

open access: yes, 2012
Includes abstract.Includes bibliographical references.Hearing aid fitting is a costly process due to the cost of hearing aids, audiologists' hourly rates, and large travelling distances caused by regionally sparse audiologist populations.
Moore, Calvin
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Cubic Spline Curve Fitting with Controlled End Conditions

open access: yes, 1974
Another method for cubic spline curve fitting. It is a more flexible version of a proven technique by using a set of end conditions suggested by Nutbourne.
J.A. Adams
core  

Fatigue Analyses of a Flexible Riser Considering End Fitting Effects

open access: yes, 2017
During the end fitting (EF) mounting process, the tensile armor wires of flexible pipes are folded and then unfolded. This process usually leaves plastic deformations and generates sharp curvatures on these wires just at the EF entrance.
Alyson G. Vaillant   +4 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Quasi-static strengths and failure modes of tight-fitting and round-end metal-plate wooden truss joints

open access: yes, 2007
An experimental study was conducted to investigate whether existing industry design procedures for tight-fitting metal-plate-connector truss joints can be applied to the design of joints made with round-end webs.
Dadhiala, Navdeep Singh
core  

Isochrone fitting in the Gaia era

open access: yes, 2018
Context. Currently, galactic exploration is being revolutionized by a flow of new data: Gaia provides measurements of stellar distances and kinematics; growing numbers of spectroscopic surveys provide values of stellar atmospheric parameters and ...
Alexey Mints   +3 more
core   +1 more source

Fitting multiple heterogeneous models by multi-class cascaded t-linkage [PDF]

open access: yes, 2019
This paper addresses the problem of multiple models fitting in the general context where the sought structures can be described by a mixture of heterogeneous parametric models drawn from different classes. To this end, we conceive a multi-model selection
Andrea Fusiello   +5 more
core   +1 more source

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