Results 221 to 230 of about 189,790,258 (290)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Mexican Social Security Institute (IMSS) Pandemic Workforce Administrative Cohort (IMPACT): design and descriptive estimates of surveillance-detected COVID-19 outcomes and primary-series vaccination coverage. [PDF]

BMJ Public Health
Ortiz-Brizuela E, Schnitzer ME, Talbot D, Real Ornelas GA, Velasco Reyna R, Hernandez-Avila M, Carabali M.   +6 more
europepmc   +1 more source

No End of Worlds

, 2019
openaire   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

An Improved Two-Stage Planning Method for Multi-UAV Collaborative Inspection of Spatially Non-Uniform Power Grids. [PDF]

Sensors (Basel)
Ni J, Xiao Z, Zha C, Gu Y, Shi P.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

WIS: world-guided instruction semantic diffusion policy for predictive bimanual manipulation. [PDF]

Front Neurorobot
Liu X, Hou L, Cheng P, Luo X, Xie F, Wei J, Wang F, Liu A.   +7 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Real-World Implementation and Evaluation of a Digital Health Platform for Children Living With Type 1 Diabetes: Protocol for a Real-World Implementation Study. [PDF]

JMIR Res Protoc
Muralidharan S, Sweeney Magee M, Charbonneau K, McKee S, Zachariuk C, Tamana SK, Dominguez-Menendez G, Tang TS, Borycki EM, Kushniruk AW, Wasserman WW, Bone JN, Görges M, Amed S.   +13 more
europepmc   +1 more source