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End-stage liver disease in children

Current Treatment Options in Gastroenterology, 2001
The treatment of children with end-stage liver disease involves the coordinated management of nutritional deficiencies, ascites, pruritus, encephalopathy, and portal hypertension. The implementation of management strategies depends upon a parent or guardian to administer the plan in the context of a child at different stages of developmental ...
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Infections in Patients With End-stage Liver Disease

Journal of Clinical Gastroenterology, 2007
Infections in patients with end-stage liver disease (ESLD) are an important cause of morbidity and mortality in these patients. Abnormalities in their natural defense mechanisms, alterations in the enteric flora and the growing utilization of invasive procedures increase the risk of infections in these patients.
Rekha, Cheruvattath, Vijayan, Balan
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Management of End-stage Liver Disease

Medical Clinics of North America, 2014
Patients with cirrhosis who experience hepatic decompensation, such as the development of ascites, SBP, variceal hemorrhage, or hepatic encephalopathy, or who develop HCC, are at a higher risk of mortality. Management should be focused on the prevention of recurrence of complications, and these patients should be referred for consideration of liver ...
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End‐stage renal disease in liver transplants

Clinical Transplantation, 2001
Renal dysfunction is one of the most significant problems following orthotopic liver transplantation (OLTx). Since the major risk factor for delayed renal dysfunction following OLTx is presumed to be cyclosporine (CsA) nephrotoxicity, it has been suggested that CsA is the most probably cause of end‐stage renal disease (ESRD) in this population of ...
M, Lynn   +3 more
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Glomerulonephritis with end-stage liver disease in childhood

The Lancet, 1992
Renal biopsies were done perioperatively in 18 children receiving liver grafts. All specimens showed glomerulonephritis, which was mesangial-proliferative in 15 and mesangio-capillary in 3. Of the 16 children who were alive four or more months after transplantation, only 1 showed progressive deterioration of renal function; 1 other had a subnormal but ...
G, Noble-Jamieson   +4 more
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End stage liver disease

Paediatrics and Child Health, 2013
Abstract Around 1200 children in the UK are under surveillance after liver transplantation for end stage liver disease (ESLD) and about 600 additional children have ESLD, but are not yet in need of transplantation. ESLD occurs in the context of extensive structural liver damage in which blood flow through the sinusoids, and the production and ...
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Nutrition Support in End-Stage Liver Disease

Critical Care Nursing Clinics of North America, 2010
Protein-calorie malnutrition is common in end-stage liver disease, irrespective of cause, and adversely affects clinical outcomes. Early diagnosis is important to allow appropriate intervention to prevent malnutrition-associated complications. Correction of nutrient deficiencies through oral supplementation, enteral tube feeding, or parenteral feeding ...
Vivian M, Zhao, Thomas R, Ziegler
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Hepatitis B and End-Stage Liver Disease

Clinics in Liver Disease, 2007
Hepatitis B virus (HBV) is the most common cause of chronic hepatitis and end-stage liver disease worldwide. Untreated, chronic hepatitis B acquired early in life results in cirrhosis, liver failure, or hepatocellular carcinoma in up to 40% of individuals.
Ilan S, Weisberg   +2 more
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The treatment of end‐stage liver disease in childhood

Journal of Paediatrics and Child Health, 1988
With the availability of orthotopic liver transplantation as a definitive treatment option for most cases of end-stage liver disease in children, there is renewed interest in this hitherto universally fatal condition. The potential for long-term survival after liver transplantation without disability is a realistic prospect for the majority, although ...
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Nutrition in pediatric end-stage liver disease

Current Opinion in Clinical Nutrition & Metabolic Care
Purpose of review The aim of this review is to outline recent studies relating to nutritional status and outcomes in pediatric end-stage liver disease. Main findings Pediatric patients with chronic and end-stage liver disease are at high risk of malnutrition. Given additional growth
Tejas S, Desai   +3 more
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