Results 201 to 210 of about 590,509 (328)

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

open access: yesAdvanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin   +6 more
wiley   +1 more source

Fatal adenovirus meningoencephalitis in end stage renal disease patient

open access: yesInternational Journal of Infectious Diseases, 2020
X.K. Cheong   +6 more
doaj   +1 more source

Progressive painful skin lesions in a patient with end-stage renal disease. [PDF]

open access: yesJAAD Case Rep
Daniels P   +5 more
europepmc   +1 more source

Systemic immune‑inflammation index predicts a reduced risk of end‑stage renal disease in Chinese patients with myeloperoxidase‑anti‑neutrophil cytoplasmic antibody‑associated vasculitis: A retrospective observational study

open access: diamond, 2021
Jinbiao Chen   +15 more
openalex   +2 more sources

TREM2 Drives Neutrophil Extracellular Traps‐Induced Dendritic Cell Maturation and Contributes to Lupus Progression

open access: yesAdvanced Science, EarlyView.
TREM2 recognizes NETs‐derived MPO to promote DC maturation and antigen presentation, thereby exacerbating the autoimmune response in SLE. Mechanistically, TREM2 activation triggers the DAP12/SYK/ERK cascade and enhances NETs internalization by DCs, which in turn activates the cGAS/STING signaling pathway.
Jingxian Shu   +7 more
wiley   +1 more source

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