Results 201 to 210 of about 315,907 (248)

Genetic and Functional Evidence Links Germline Biallelic Inactivating Variants in WWOX to Histological Mixed‐Type Thyroid Cancer

Advanced Science, EarlyView.
The role of germline WWOX loss‐of‐function variants in oncogenesis has remained poorly characterized. This study provides the first comprehensive genetic and functional evidence that such variants promote tumorigenesis through the disruption of multiple tumor‐suppressive mechanisms.
Xiaopeng Zhang, Jian Qi, Jialiang Wang, Zhipeng Wang, Yongguang Wang, Zongtao Hu, Ao Xu, Bo Hong, Hongzhi Wang   +8 more
wiley   +1 more source

Probiotics restore enteric HDL3 secretion and improve prognosis in patients with end-stage renal disease. [PDF]

Imeta
Liu X, Huang Y, Li Y, Chen J, Wang X, Wang X, Zhao L, Luo Y, An P, Zhang L, Zhang C, Bian W, Lei X, Gao X, Liu Y, Hao Y, Guo H, Zhang X, Wang P, Wang R, Zhang H, Fang B, Zhang X, Wang L, Qiu Q, Zhang Y, Qi J, Yang S, Yin Y, Ren F, Wang X.   +30 more
europepmc   +1 more source

Survival of patients treated for end-stage renal disease by dialysis and transplantation.

, 1977
Michael R. Higgins, Michael Grace, John B. Dossetor   +2 more
openalex   +1 more source

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

Comparative risk of end-stage renal disease, myocardial infarction and stroke in young and older onset diabetes in UK Biobank. [PDF]

Sci Rep
Kar D, Molokhia M, Wierzbicki A, Koziell A, Byng R, Spicer S, Farina N, Pinkney J, Song S, Zabeen B, Kar S, Jonnagaddala J, Liaw ST, El-Wazir A, Nath M, Khan MAB, Sheikh A, de Lusignan S.   +17 more
europepmc   +1 more source

422 The novel concept of personalized decremental home hemodialysis following successful bariatric surgery in end stage renal disease

openalex   +1 more source

Nanofluid‐Enhanced Laser Lithotripsy Using Conducting Polymer Nanoparticles

Advanced Science, EarlyView.
Incorporating polymeric nanoparticles, PEDOT:PSS, with a high near‐infrared absorption coefficient into the fluid significantly enhances the dusting efficiency of Ho:YAG laser lithotripsy for kidney stone treatment. This approach, which leverages the control of light‐matter interactions, integrates seamlessly with the current laser lithotripsy workflow.
Qingsong Fan, Junqin Chen, Arpit Mishra, Aaron Stewart, Faisal Anees, Ting‐Hsuan Chen, Judith Dominguez, Christine Payne, Michael E. Lipkin, Pei Zhong, Po‐Chun Hsu   +10 more
wiley   +1 more source

Correlation analysis of anxiety, depression, and sleep quality in end-stage renal disease patients undergoing maintenance hemodialysis. [PDF]

Medicine (Baltimore)
Du Z, Chu T, Dai F, Mao H, Zhao J.
europepmc   +1 more source

Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer

Advanced Science, EarlyView.
An integrative analysis combining in vitro genome‐wide immune screens, in vivo ICB screens, and clinical data mining identifies METTL5 as a key tumor‐intrinsic immune factor. Mechanistic studies further reveal the importance of the METTL5‐ATF4‐SLC7A11/SLC3A2‐ferroptosis axis in modulating antitumor immune responses. These findings highlight METTL5 as a
Jiakai Hou, Cheng‐Wei Ju, Nicholas A. Egan, Yanjun Wei, Yunfei Wang, Minghao Dang, Tianyi Zhou, Leilei Shi, Ningbo Zheng, Si Chen, Ashley M. Guerrero, Xiaofang Liang, Wanfu Wu, Areej Akhtar, Chitra Dhiman, Debanwita Roy Burman, Andro E. Gerges, Mason D. Flores, Han Li, Li‐Sheng Zhang, Marleen Kok, Xiaobo Mao, Linghua Wang, Qin Feng, Yiwen Chen, Sanghoon Lee, Daniel J. McGrail, Nidhi Sahni, Chuan He, Amir A. Jazaeri, Weiyi Peng   +30 more
wiley   +1 more source

Whole-exome sequencing of kidney transplant recipients and donors: insights into end-stage renal disease and post-transplant genetic risk. [PDF]

BMC Nephrol
Bayanova M, Bolatov A, Malik D, Sapargaliyeva M, Abdikadirova A, Zhenissova A, Nazarova L, Assykbayev M, Abdugafarov S, Rakhimzhanova S, Suleimenova D, Kuttymuratov G, Ainakulov A, Sailybayeva A, Altynova S, Pya Y.   +15 more
europepmc   +1 more source