Results 61 to 70 of about 552,950 (234)

Dynamism in the 20th-Century Worldview and Linguistic Science

Linguaculture
The task of any scientific endeavour is to come up with an objective and accurate account of a specific segment of reality. However, this intended accuracy has become quite a challenge in the (post)modern era, especially in humanities.
Cătălin Nicolau
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Phylogenetic analysis reveals a correlation between the expansion of very virulent infectious bursal disease virus and reassortment of its genome segment B [PDF]

, 2006
Infectious bursa] disease virus (IBDV) is a birnavirus causing immunosuppressive disease in chickens. Emergence of the very virulent form of IBDV (vvIBDV) in the late 1980s dramatically changed the epidemiology of the disease.
Lam, PY, Ng, PTW, Lam, TY, Lam, Tsan-Yuk, Rambaut, Andrew, Drummond, A, Zeng, F, Drummond, Alexei, Lee, Yiu-Fai, Yip, Chi-Wai, Leung, Frederick C. C., Rambaut, A, Zeng, Fanya, Hon, CC, Lam, Pui-Yi, Ng, Patrick T. W., Lee, YF, Hon, Chung-Chau, Yip, CW, Leung, FCC   +19 more
core   +1 more source

(RE)CREATING NEW BODIES OF WORK: THE TEACHING OF LITERARY TRANSLATION IN CHINESE STUDIES, AND THE NEW TRANSLATIONAL STRATEGIES

Filolog
With China’s growing economic and cultural presence in recent years, translation of Chinese literature has been recognized as an important cross-cultural effort both in China and the global sinological circles.
Zoran G. Skrobanović, Mirjana M. Pavlović   +1 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Farewelling the Endeavour.

, 1996
The Sisters from Whitby, staff and students lined Fremantle wharf to farewell ""Endeavour"" for its trip to Whitby on 16/10 ...

core  

Subject-specific body segment parameters' estimation using biplanar X-rays: a feasibility study [PDF]

, 2010
In order to improve the reliability of children's models, the aim of this study was to determine the subject-specific masses and 3D locations of the centres of mass (CoM) of body segments using biplanar X-rays.
Sébastien Laporte, Mitton, David, David Mitton, Baptiste Sandoz, Wafa Skalli, Sandoz, Baptiste, Skalli, Wafa, Laporte, Sebastien   +7 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source