Results 171 to 180 of about 232,181 (311)

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

Vaccination for communicable endemic diseases: optimal allocation of initial and booster vaccine doses. [PDF]

J Math Biol
Rao IJ, Brandeau ML.
europepmc   +1 more source

Participatory epidemiology of endemic diseases in West African cattle - Ethnoveterinary and bioveterinary knowledge in Fulani disease control. [PDF]

One Health, 2018
Majekodunmi AO, Dongkum C, Idehen C, Langs DT, Welburn SC.   +4 more
europepmc   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Cost-effectiveness of sentinel screening of endemic diseases alongside malaria diagnosis: A case study in schistosomiasis. [PDF]

PLoS Negl Trop Dis
Manca F, Ciminata G, Grieve E, Reboud J, Cooper J, McIntosh E.   +5 more
europepmc   +1 more source

Common mental disorders among workers chronically exposed to pesticides: the case of workers involved in fighting endemic diseases. [PDF]

Rev Bras Med Trab, 2019
Bastos MLA, de Carvalho MCL, Ferreira MJM, Freitas TH, da Silva-Junior GB.   +4 more
europepmc   +1 more source

Investigating Tuberculosis Dynamics Under Various Control Strategies: A Comprehensive Analysis Using Real Statistical Data

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat, Mahmoud H. DarAssi, Irfan Ahmad, Muhammad Altaf Khan, Reem Algethamie   +4 more
wiley   +1 more source

Resilient Hearts: A Journey of Battling Endemic Diseases in Lyari Town. [PDF]

Am J Trop Med Hyg
Khenhrani RR.
europepmc   +1 more source

Outcomes From Using Mortality, Antimicrobial Consumption, and Vaccine Use Data for Monitoring Endemic Diseases in Danish Swine Herds. [PDF]

Front Vet Sci, 2019
Lopes Antunes AC, Jensen VF, Toft N.
europepmc   +1 more source

Fractional Moment Theory for Anomalous Transport: A Unified Framework for Lévy Flights, Fractals, and Complex Dynamical Systems

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT We develop a unified mathematical framework extending classical moment theory from discrete integer orders to a continuous spectrum of real orders f>0$$ f>0 $$, providing a systematic statistical characterization of complex systems exhibiting power‐law behavior.
Farrukh A. Chishtie
wiley   +1 more source