Results 41 to 50 of about 176,467 (264)

Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1

Advanced Science, EarlyView.
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang, Yi Liu, Zhiying Yao, Haolong Lai, Xiaoxin Chen, Ziqiu Wang, Yiqiong Bao, Tingting Li, Xiaoming Zhou, Xiabin Chen, Peiguo Yang   +10 more
wiley   +1 more source

Multicohort Validation of Gut Microbiome Signatures for Cholangiocarcinoma Diagnosis and Functional Characterization of Bifidobacterium Pseudocatenulatum

Advanced Science, EarlyView.
This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao, Jianwen Jiang, Ruiqing Zhang, Dongya Zhang, Chenchen Zhang, Ang Li, Haifeng Lu, Hua Zhang, Lin Zhou, Wenzhi Guo, Peihao Wen, Jianfeng Xue, Jie Pan, Tuerganaili Aji, Zhou Lan, Xianzhi Jiang, Shusen Zheng, Zujiang Yu, Zhigang Ren   +18 more
wiley   +1 more source

Antimicrobial Activity of Three Endemic Verbascum Species

Pharmaceutical Biology, 2002
The extracts obtained from three Verbascum L. species (Verbascum olympicum Boiss., Verbascum prusianum Boiss., and Verbascum bombyciferum Boiss.) have been investigated for their antimicrobial activity. Growth inhibition, using the agar disc diffusion assay, was determined against Escherichia coli ATCC 11230, Micrococcus luteus La 2971, Staphylococcus ...
Guleryuz, GÜRCAN, Kirmizi, SERAP, Arslan, H, Dulger, B   +3 more
openaire   +2 more sources

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

Advanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao, Victor Fernandez‐Gonzalez, Xiaochuan Wang, Blake Pylipow, Claudia Herrera, Xiaohu Xia   +5 more
wiley   +1 more source

Machine Learning‐Augmented Loop‐Mediated Isothermal Amplification‐Enabled Point‐of‐Care for Mpox‐Specific Detection

Advanced Intelligent Systems, EarlyView.
A low‐cost, portable point‐of‐care platform for rapid Mpox detection using loop‐mediated isothermal amplification is reported. The device integrates fluorescence readout and mobile monitoring. A machine‐learning model analyzes temperature data and correlates thermal changes with DNA concentration, enabling sensitive and reliable molecular diagnosis in ...
Nazente Atceken, Ahmed Choukri Abdullah, Olgac Ozarslan, Ziya Yıldız, Savas Tasoglu   +4 more
wiley   +1 more source

Causal analysis of trade loss from pathogens: A global study of foot and mouth disease impacts on meat exports

American Journal of Agricultural Economics, EarlyView.
Abstract Our general interest is in global trade loss from livestock pathogens, specifically exports. We adopt a causal inference approach that considers animal disease outbreaks over time as non‐staggered binary treatments with the potential for switching in (infection) and out of treatment (recovery) within the sample period. The outcome evolution of
Mohammad Maksudur Rahman, Thomas L. Marsh   +1 more
wiley   +1 more source

Endemic species of terrestrial isopods (Isopoda, Crustacea) in the Romanian fauna

Studia Universitatis Babeș-Bolyai. Biologia, 2018
In the Romanian fauna 32 endemic species of terrestrial isopods were described; most of them are epigenous, few are troglobiont, troglophilous and edaphic species.
Nicolae TOMESCU
doaj   +1 more source

Shaped by context: Evolutionary trajectories of desiccation tolerance in land plants

American Journal of Botany, EarlyView.
Abstract Desiccation tolerance (DT), the ability to survive near‐complete cellular dehydration, is widespread in diaspores but rare in the vegetative tissues of land plants. The patchy and punctuated phylogenetic distribution of vegetative desiccation tolerance (VDT) suggests that the trait is both ancient and recurrent, yet the evolutionary ...
Rose A. Marks, R. Shawn Abrahams, Jenna T. B. Ekwealor   +2 more
wiley   +1 more source

Endemic fish species structuring oceanic intertidal reef assemblages [PDF]

Scientific Reports, 2018
AbstractIntertidal reef environments are facing a global crisis as climate changes are causing sea-level rise. Synergistically, other human-induced impacts (e.g., sewage, habitat loss) caused by concentration of human populations near the coast increase the natural vulnerability of intertidal ecosystems.
Ryan Andrades, José Amorim Reis-Filho, Raphael M. Macieira, Tommaso Giarrizzo, Jean-Christophe Joyeux   +4 more
openaire   +2 more sources

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

Animal Models and Experimental Medicine, EarlyView.
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei, Jing Wu, Hekai Yang, Na Li, Binbin Zhao, Wanjun Peng, Na Rong, Wei Zhang, Jing Xue, Jiangning Liu   +9 more
wiley   +1 more source