Results 161 to 170 of about 159,577 (267)

Synthesis of Rhodamine TEMPO Conjugates via Isonitrile‐Based Multicomponent‐Reactions for Mitochondria‐Targeted ROS‐Detection in Cancer Cells

open access: yesAdvanced Sensor Research, EarlyView.
This article explores the development of rhodamine TEMPO conjugates via the Ugi‐multicomponent reaction to detect reactive oxygen species (ROS) in living cells. The sensors are highly selective for mitochondria in both cancer and normal cell lines, with fluorescence quenching and EPR spectroscopy offering precise ROS detection.
Haider N. Sultani   +6 more
wiley   +1 more source

High‐Sensitivity Dopamine Detection with Copper Terephthalate‐Modified Carbon Electrode

open access: yesAdvanced Sensor Research, EarlyView.
This work introduces a facile synthesis of a copper‐terephthalate with a flake‐like morphology and layered topology. The Cu‐BDC demonstrates exceptional performance as a glassy carbon electrode modifier, enabling highly sensitive and reliable dopamine detection.
Aleksander Ejsmont   +3 more
wiley   +1 more source

On the Relentless Pursuit of an Oral Insulin Delivery System: How Far is Too Far?

open access: yesAdvanced Therapeutics, EarlyView.
Injectable insulin preparations have far outpaced oral ones by virtue of adequate bioavailability and are driven by innovations, including insulin pumps, real‐time blood glucose monitoring, and artificial intelligence. In contrast, oral insulin delivery systems, including nanomedicines, continue to struggle and lag due to varied reasons.
Sourav Bhattacharjee
wiley   +1 more source

LightRoseTTA: High‐Efficient and Accurate Protein Structure Prediction Using a Light‐Weight Deep Graph Model

open access: yesAdvanced Science, EarlyView.
Accurately predicting protein structure is of great significance in biological research. LightRoseTTA, a light‐weight deep graph network, to achieve prediction for proteins is presented. Notably, three highlights are possessed by LightRoseTTA: i) high‐accurate structure prediction for proteins; ii) high‐efficient training and inference; and iii) low ...
Xudong Wang   +7 more
wiley   +1 more source

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