Results 41 to 50 of about 9,843,586 (391)

Bulk and single-cell transcriptome analyses of islet tissue unravel gene signatures associated with pyroptosis and immune infiltration in type 2 diabetes

open access: yesFrontiers in Endocrinology, 2023
IntroductionType 2 diabetes (T2D) is a common chronic heterogeneous metabolic disorder. However, the roles of pyroptosis and infiltrating immune cells in islet dysfunction of patients with T2D have yet to be explored.
Yaxian Song   +7 more
doaj   +1 more source

Mutations of the ret protooncogene in German multiple endocrine neoplasia families: Relation between genotype and phenotype. [PDF]

open access: yes, 1996
It has been suggested that not only the position but also the nature of the mutations of the ret protooncogene strongly correlate with the clinical manifestation of the multiple endocrine neoplasm type 2 (MEN 2) syndrome.
Deckart, H. F.   +15 more
core   +1 more source

MANAGEMENT OF ENDOCRINE DISEASE: Diagnosis and management of primary aldosteronism: the Endocrine Society guideline 2016 revisited.

open access: yesEuropean Journal of Endocrinology, 2018
The syndrome of primary aldosteronism (PA) is characterized by hypertension with excessive, autonomous aldosterone production and is usually caused by either a unilateral aldosterone-producing adenoma or bilateral adrenal hyperplasia.
T. Williams, M. Reincke
semanticscholar   +1 more source

Practical tools to identify short children born small-for-gestational-age eligible for rhGH treatment according to Italian regulation

open access: yesItalian Journal of Pediatrics, 2019
Recombinant human growth hormone (rhGH) is an approved and effective treatment for short children born small for gestational age (SGA). Prevalence of children eligible for treatment as SGA is reported to be 1:1800.
Gianluca Tornese   +6 more
doaj   +1 more source

Environmental chemical exposures and breast cancer [PDF]

open access: yes, 2016
As a hormone-sensitive condition with no single identifiable cause, breast cancer is a major health problem. It is characterized by a wide range of contributing factors and exposures occurring in different combinations and strengths across a lifetime ...
Plant, J, Stanley, E, Voulvoulis, N
core   +2 more sources

DIAGNOSIS OF ENDOCRINE DISEASE: Congenital hypothyroidism: update and perspectives

open access: yesEuropean Journal of Endocrinology, 2018
Congenital hypothyroidism (CH) may be primary, due to a defect affecting the thyroid gland itself, or central, due to impaired thyroid-stimulating hormone (TSH)-mediated stimulation of the thyroid gland as a result of hypothalamic or pituitary pathology.
Catherine Peters   +2 more
semanticscholar   +1 more source

Genetics of Common Endocrine Disease: The Present and the Future.

open access: yesJ Clin Endocrinol Metab, 2016
CONTEXT In honor of the 75th issue of the Journal of Clinical Endocrinology and Metabolism, the author was invited to present his perspectives on genetics in human endocrinology.
Goodarzi MO.
europepmc   +2 more sources

The Clinical Significance of Subclinical Thyroid Dysfunction. [PDF]

open access: yes, 2008
Subclinical thyroid disease (SCTD) is defined as serum free T(4) and free T(3) levels within their respective reference ranges in the presence of abnormal serum TSH levels.
BIONDI, BERNADETTE, COOPER DS
core   +1 more source

MANAGEMENT OF ENDOCRINE DISEASE: Immune check point inhibitors-induced hypophysitis.

open access: yesEuropean Journal of Endocrinology, 2019
In recent years, the development of immunotherapy has constituted a revolution in the therapy for many cancers, with a specific toxicity profile including endocrine immune-related adverse events.
F. Albarel, F. Castinetti, T. Brue
semanticscholar   +1 more source

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