Results 51 to 60 of about 9,843,586 (391)

Clinical effectiveness and cost-effectiveness of pegvisomant for the treatment of acromegaly: a systematic review and economic evaluation [PDF]

, 2009
Background: Acromegaly, an orphan disease usually caused by a benign pituitary tumour, is characterised by hyper-secretion of growth hormone (GH) and insulin-like growth factor I (IGF-1).
A Colao, A Colao, AJ van der Lely, AL Barkan, AN Paisley, AN Paisley, AS Bates, C Parkinson, C Parkinson, C Parkinson, C Parkinson, C Parkinson, Cambridgeshire joint prescribing group decision document, D Moore, David J Moore, G Didoni, G Sesmilo, H Biering, I Schreiber, IM Holdaway, J Ayuk, J Feenstra, JO Jorgensen, Martin J Connock, NHS Centre for Reviews and Dissemination University of York, NR Biermasz, P Chanson, Pfizer Limited, PJ Trainer, R Kauppinen-Makelin, R Kauppinen-Makelin, R Pivonello, R Trepp, S Jehle, S Melmed, SC Hua, SM Orme, SM Webb, Sue Bayliss, SV Rowles, VS Bonert, Welsh Medicines Partnership, WP Fairfield, Yaser Adi   +43 more
core   +4 more sources

DIAGNOSIS OF ENDOCRINE DISEASE: Evaluation of bone fragility in endocrine disorders.

European Journal of Endocrinology, 2019
An underlying disease affecting bone health is present in up to 40% and 60% of osteoporotic post-menopausal women and men respectively. Among the disorders leading to a secondary form of osteoporosis, the endocrine diseases are highly represented.
C. Eller-Vainicher, A. Falchetti, L. Gennari, E. Cairoli, F. Bertoldo, F. Vescini, A. Scillitani, I. Chiodini   +7 more
semanticscholar   +1 more source

Identification of Biomarkers Related to Metabolically Unhealthy Obesity in Korean Obese Adolescents: A Cross-Sectional Study

Children, 2023
Background: The current study aimed to screen for relationships and different potential metabolic biomarkers involved between metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO) in adolescents.
Sarang Jeong, Han-Byul Jang, Hyo-Jin Kim, Hye-Ja Lee   +3 more
doaj   +1 more source

Clinical response to primary letrozole therapy in elderly patients with early breast cancer : possible role for p53 as a biomarker [PDF]

, 2014
Primary tamoxifen therapy has been widely used to treat elderly women with ER-positive breast cancer in the past. Aromatase inhibitors may be more beneficial than tamoxifen when used as primary endocrine therapy in elderly patients.
Agarwal, Vijay, Cawkwell, Lynn, Drew, Philip J., Fox, John N., Garimella, Veerabhadram, Hussain, Tasadooq, Kneeshaw, Peter J., Lind, Michael J., Long, Ervine D., Mahapatra, Tapan K., McManus, Penelope L., Radhakrishna, Selvi   +11 more
core   +1 more source

MANAGEMENT OF ENDOCRINE DISEASE: Therapeutics of Vitamin D.

European Journal of Endocrinology, 2018
Objective The central role of vitamin D in bone health is well recognized. However, controversies regarding its clinical application remain. We therefore aimed to review the definition of hypovitaminosis D, the skeletal and extra-skeletal effects of ...
Peter R. Ebeling, Robert A. Adler, Glenville Jones, Uri A. Liberman, G. Mazziotti, S. Minisola, Craig F. Munns, N. Napoli, A. Pittas, Andrea Giustina, J. Bilezikian, R. Rizzoli   +11 more
semanticscholar   +1 more source

Pasireotide-Induced Shrinkage in GH and ACTH Secreting Pituitary Adenoma: A Systematic Review and Meta-Analysis

Frontiers in Endocrinology, 2022
IntroductionPasireotide (PAS) is a novel somatostatin receptor ligands (SRL), used in controlling hormonal hypersecretion in both acromegaly and Cushing’s Disease (CD). In previous studies and meta-analysis, first-generation SRLs were reported to be able
Alessandro Mondin, Alessandro Mondin, Renzo Manara, Renzo Manara, Giacomo Voltan, Giacomo Voltan, Irene Tizianel, Irene Tizianel, Luca Denaro, Luca Denaro, Marco Ferrari, Marco Ferrari, Mattia Barbot, Mattia Barbot, Carla Scaroni, Carla Scaroni, Filippo Ceccato, Filippo Ceccato   +17 more
doaj   +1 more source

Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]

, 2013
Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher, Solomon, Daniel, Sosa, Julie Ann, Tuggle, Charles   +3 more
core   +1 more source

Vitamin D for the Prevention of Disease: An Endocrine Society Clinical Practice Guideline.

Journal of Clinical Endocrinology and Metabolism
BACKGROUND Numerous studies demonstrate associations between serum concentrations of 25-hydroxyvitamin D (25[OH]D) and a variety of common disorders, including musculoskeletal, metabolic, cardiovascular, malignant, autoimmune, and infectious diseases ...
M. Demay, A. Pittas, Daniel D Bikle, Dima L. Diab, Mairead E Kiely, M. Lazaretti-Castro, Paul Lips, Deborah M Mitchell, M. H. Murad, Shelley Powers, S. Rao, R. Scragg, J. Tayek, A. Valent, J. Walsh, Christopher R McCartney   +15 more
semanticscholar   +1 more source

Triple positive breast cancer. A distinct subtype? [PDF]

, 2015
Breast cancer is a heterogeneous disease, and within the HER-2 positive subtype this is highly exemplified by the presence of substantial phenotypical and clinical heterogeneity, mostly related to hormonal receptor (HR) expression.
A. Cassano, A. Michelotti, C. Botti, C. Natoli, D. Sergi, F. Conti, F. Izzo, I. Sperduti, L. D'Onofrio, L. D. Lauro, L. Mariani, L. Moscetti, L. Pizzuti, M. Barba, M. Maugeri Saccà, M. Mottolese, MARCHETTI, PAOLO, P. Vici, T. Gamucci, V. Rossi   +19 more
core   +1 more source

Treatment of endocrine diseases. [PDF]

BMJ, 1987
Conn's syndrome, is rare but may be suspected in patients with hypertension and hypokalaemia. The hypertension is rarely severe and full investigation may be postponed until after pregnancy, when localisation procedures such as the use of radio labelled selenium cholesterol may be used without fear of affecting the fetus. Cushing's syndrome?Though rare,
openaire   +3 more sources