Results 141 to 150 of about 34,824 (338)
Advanced Healthcare Materials, EarlyView.Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis +19 more
wiley +1 more source
2,4-Dichlorophenol Shows Estrogenic Endocrine Disruptor Activity by Altering Male Rat Sexual Behavior. [PDF]
Toxics, 2023 Ferris Pasquini V +3 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu +10 more
wiley +1 more source
Ecotoxicity of substances with hormonal effect [PDF]
, 2010 Tato bakalářská práce se zabývá osudem a ekotoxicitou vybraných látek s hormonálním účinkem v životním prostředí. Jsou to nejen látky ze skupiny steroidních hormonů, které jsou pro tento účinek vyráběny, ale také mnoho xenobiotik, které tento účinek ...
Cvikýřová, Zuzana
core
BPA Endocrine Disruptor Detection at the Cutting Edge: FPIA and ELISA Immunoassays. [PDF]
Biosensors (Basel), 2023 Raysyan A +3 more
europepmc +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Advances in Bioprinting to Model Immune‐Mediated Skin Diseases
Advanced Healthcare Materials, EarlyView.This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández +4 more
wiley +1 more source
Effects of an Endocrine Disruptor Triclosan on Ruditapes decussatus: Multimarker and Histological Approaches. [PDF]
Animals (Basel), 2023 Added A +9 more
europepmc +1 more source