Results 241 to 250 of about 22,130 (290)
Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone
Advanced Science, EarlyView.In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman +15 more
wiley +1 more source
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2013
Abstract Endocrine disruptors are synthetic chemicals that interfere with the function of natural hormones. Endocrine-disrupting chemicals have become ubiquitous in the modern environment. They can affect human health and development—especially reproductive and cognitive development—even at very low levels of exposure.
Annemarie Stroustrup, Shanna H. Swan
+4 more sources
Abstract Endocrine disruptors are synthetic chemicals that interfere with the function of natural hormones. Endocrine-disrupting chemicals have become ubiquitous in the modern environment. They can affect human health and development—especially reproductive and cognitive development—even at very low levels of exposure.
Annemarie Stroustrup, Shanna H. Swan
+4 more sources
Endocrine disruptors and endometriosis
Reproductive Toxicology, 2023Endometriosis is a hormone-dependent inflammatory gynecological disease of reproductive-age women. It is clinically and pathologically characterized by the presence of functional endometrium as heterogeneous lesions outside the uterine cavity. The two major symptoms are chronic pelvic pain and infertility, which profoundly affect women's reproductive ...
Sudipta, Dutta +2 more
openaire +2 more sources
2011
Abstract During the past 50 years, there has been a huge increase in the number of chemical substances used worldwide as plasticizers, pesticides, detergents, paints, metal food cans, flame retardants, cosmetics, and chemical wastes, which exhibit the potential to interfere with the endocrine system of humans and animals. In addition, it
George Creatsas, George Mastorakos
openaire +2 more sources
Abstract During the past 50 years, there has been a huge increase in the number of chemical substances used worldwide as plasticizers, pesticides, detergents, paints, metal food cans, flame retardants, cosmetics, and chemical wastes, which exhibit the potential to interfere with the endocrine system of humans and animals. In addition, it
George Creatsas, George Mastorakos
openaire +2 more sources
Endocrine disruptor global policy
2021Over the past several decades, scientific consensus has grown around the concept and evidence for human health impacts from exposure to endocrine disrupting chemicals (EDCs). A series of publications have now demonstrated considerable economic costs of EDC exposure-induced adverse health outcomes.
Christopher D, Kassotis +1 more
openaire +2 more sources
Journal of Pediatric Endocrinology and Metabolism, 2005
Man does not come into the world pre-determined. The lifetime set of environmental conditions impinging on a given individual has been termed the ambiome, which together with the genome and the proteome determines each individual's development and construction. Among the most important elements making up the ambiome are endocrine disruptors.
M, Pombo, L, Castro-Feijóo
openaire +2 more sources
Man does not come into the world pre-determined. The lifetime set of environmental conditions impinging on a given individual has been termed the ambiome, which together with the genome and the proteome determines each individual's development and construction. Among the most important elements making up the ambiome are endocrine disruptors.
M, Pombo, L, Castro-Feijóo
openaire +2 more sources