Design and prioritization of the French surveillance program of health effects in the context of exposure to endocrine disruptors using a Delphi study. [PDF]
Peyronnet A +5 more
europepmc +1 more source
In maize, the bHLH transcription factor ZmbHLH118 directly binds to the promoter of ZmCLCa and inhibits its expression. Tonoplast‐localized ZmCLCa mediates NO3− influx into the vacuole to regulate intracellular NO3− homeostasis, modulating nitrate uptake and metabolism, plant growth, and grain yield.
Chaonan Zhang +13 more
wiley +1 more source
Distribution and Health Risk Assessment of Triclosan and Other Typical Endocrine Disruptors in Honey. [PDF]
Wang J +5 more
europepmc +1 more source
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
Editorial: Endocrine disruptors in molecular and structural endocrinology. [PDF]
Hall JM.
europepmc +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Machine learning-driven prediction models and mechanistic insights into cardiovascular diseases: deciphering the environmental endocrine disruptors nexus. [PDF]
Yu WM +6 more
europepmc +1 more source
H2S‐Releasing Aspirin Nanoparticles Alleviate Endometriosis and Associated Anxiety
Albumin nanoparticles loaded with an H2S‐releasing aspirin derivative (ACS14) hitchhiking neutrophils after intraperitoneal injection and preferentially accumulate in endometriosis lesions in mice. The treatment suppresses lesion growth by regulating PI3K/Akt and reduces inflammation by inhibiting NF‐κB.
Mengni Zhou +12 more
wiley +1 more source
Hashimoto’s encephalopathy: an endocrinological point of view
Laura Croce +6 more
doaj +1 more source

