Results 221 to 230 of about 796,161 (328)

Susceptible periods during embryogenesis of the heart and endocrine glands.

, 2000
T. W. Sadler
openalex   +1 more source

Adipose Tissue Macrophages as Initiators of Exacerbated Periodontitis in Estrogen‐Deficient Environments via the Amplifier Extracellular Vesicles

Advanced Science, EarlyView.
Chronic systemic inflammation, worsened by estrogen deficiency, underlies and exacerbates periodontitis. Proinflammatory macrophages within visceral adipose tissue are hyperactivated due to hyper‐DNA methylation, releasing small extracellular vesicles (sEVs) similar to those of their parent cells.
Danfeng Li, Tian Yang, Yuqian Li, Xinwei Lyu, Cheng Hu, Jiayin Yan, Jiali Tan   +6 more
wiley   +1 more source

Endothelial‐Derived CCL7 Promotes Macrophage Polarization and Aggravates Septic Acute Lung Injury via CCR1‐Mediated STAT1 Succinylation

Advanced Science, EarlyView.
During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li, Yuqin Long, Yunxi Zhu, Jiahui Gu, Ping Zhou, Changhong Miao   +5 more
wiley   +1 more source

An insulin-like peptide specific for a cockroach male reproductive gland. [PDF]

PLoS One
Pagone V, Pujal D, Maestro JL.
europepmc   +1 more source

Engineering Decavalent, Sperm‐Binding Laminin‐IgG Hybrid Antibodies for Potent Non‐Hormonal Contraception

Advanced Science, EarlyView.
This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer, Keiichiro Kushiro, Bhawana Shrestha, Yong Zhu, Alysha Panjwani, Lauren Dawson, Haley Flowers, Kathleen L. Vincent, Samuel K. Lai   +8 more
wiley   +1 more source

Propolis mitigates histopathological alterations in the pituitary gland and reproductive system of female albino rats subjected to cadmium toxicity. [PDF]

Vet World
Albishtue AA, Mohsin Al-Mahmmodi A, Almamoori HA, Alahmer MA.   +3 more
europepmc   +1 more source

Effects of Endocrine Disruptors on the Pituitary Gland.

, 2001
Nariaki Fujimoto
openalex   +2 more sources

Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep

Advanced Science, EarlyView.
The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu, Na Zhang, Zilong Wen, Haitao Wang, Tingting Li, Runlin Ma, Menghua Li, Daxiang Wang, Haiping Shu, Xun Huang, Jianlin Han, Yiqiang Zhao, Qiuyue Liu   +12 more
wiley   +1 more source

Recent advances in the study of reproductive function in pediatric patients with brain tumors. [PDF]

Front Pediatr
Zhang R, Liu L, Dai X, Ju Y, Ren Y.
europepmc   +1 more source

Peptide Hormone‐Mediated Regulation of Plant Development and Environmental Adaptability

Advanced Science, EarlyView.
In this review, recent advances in understanding the roles of plant peptide hormones in regulating growth, reproduction, and environmental adaptability are systematically summarized. It further elucidates the challenges in studying these peptides, such as their low abundance, functional redundancy, and complex signaling mechanisms, and highlights their
Xin Li, Liping Zhu, Huiqin Wang, Xin Zhou, Manhong Wang, Libei Li, Feng Liu, Jie Sun, Guanghui Xiao   +8 more
wiley   +1 more source