Results 281 to 290 of about 931,208 (372)

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

Advanced Science, EarlyView.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan, Wentao Gong, Xiaodian Cai, Jinyan Teng, Jiali Cai, Haonan Zeng, Wondossen Ayalew, Qingpeng Shen, Zhanming Zhong, Yifei Wang, Wenjing Zhang, Yuhan Tian, Dantong Xu, Yahui Gao, Hongwei Yin, Yuebo Zhang, Jiahui Hou, Tianru Zhou, Jiaqi Li, Lingzhao Fang, Xiaolong Yuan, Zhe Zhang   +21 more
wiley   +1 more source

Persistently elevated procalcitonin leading to the diagnosis of medullary thyroid carcinoma: a surgical case report. [PDF]

J Surg Case Rep
Caruso E, Fava A, Bonadio G, Schicchi G, Pellegrino R, Tedesco V, Gabriele C, Strangis L, Ibba F, Gambardella D, Tedesco M.   +10 more
europepmc   +1 more source

STUDIES ON THE PHYSIOLOGICAL CHEMISTRY OF THE SALIVARY GLANDS XLVI ON THE FUNCTIONAL CORRELATION BETWEEN SALIVARY GLANDS AND OTHER ENDOCRINE ORGANS II THE EFFECTS OF SOME ANTITHYROID DRUGS ON THE SALIVARY GLANDS OF RATS

, 1960
Yosoji Ito, JUN KAWADA, MUNETSUGU KURATA
openalex   +2 more sources

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

Reassessing optimal laryngeal nerve protection strategies in neck endocrine surgery: intermittent versus continuous neuromonitoring. [PDF]

Gland Surg
Sinclair C.
europepmc   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Not So Fast: Incomplete Assumptions of Adverse Thyroid Effects from PFAS Exposure. [PDF]

Environ Sci Technol
Leung AM, Pearce EN, Brent GA, Köhrle J.   +3 more
europepmc   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Endocrine disrupting chemicals and the adrenal gland. [PDF]

Turk J Med Sci
Şimşek Bağir G, Ertörer ME.
europepmc   +1 more source

Acquired tolerance to homologous transplantation of endocrine glands in inbred strains of mice.

, 1958
Carlos Alberto Martínez, June Smith, R. A. Good   +2 more
openalex   +1 more source