Results 161 to 170 of about 110,436 (285)

Mechanical Cues Regulate Cargo Sorting and Export at the Golgi

open access: yesAdvanced Science, EarlyView.
A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino   +21 more
wiley   +1 more source

Multiple endocrine glands insufficiency due to langerhans cell histiocytosis (LCH): a case report [PDF]

open access: yesInt J Pediatr Endocrinol, 2015
Mai D   +5 more
europepmc   +1 more source

Adenylosuccinate Synthase 1 Deficiency Improves Energy Metabolism by Promoting Adipose Tissue Re‐esterification via Glycerol Kinase Upregulation

open access: yesAdvanced Science, EarlyView.
Working model of Adss1‐mediated regulation of energy metabolism in adipose tissue. In beige adipocytes, Adss1 interacts with HDAC3 in the cytoplasm, and its loss reduces nuclear HDAC3 while increasing cytosolic fractions. This redistribution suppresses HDAC activity and enhances H3K27 acetylation at the Gk promoter, leading to transcriptional ...
Jingjing Sun   +16 more
wiley   +1 more source

P2X receptor channels in endocrine glands. [PDF]

open access: yesWiley Interdiscip Rev Membr Transp Signal, 2013
Stojilkovic SS, Zemkova H.
europepmc   +1 more source

Disruption of Gut Microbiota‐Mediated De Novo NAD+ Synthesis Contributes to the Development of Polycystic Ovary Syndrome

open access: yesAdvanced Science, EarlyView.
This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen   +6 more
wiley   +1 more source

A rare case of supernumerary and ectopic parathyroid adenoma in the parotid gland: diagnostic and surgical challenges. [PDF]

open access: yesDiagn Pathol
Gervasi R   +8 more
europepmc   +1 more source

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