Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé+5 more
wiley +1 more source
Hyperparathyroidism-Jaw Tumor Syndrome Associated to a CDC73 Gene Pathogenic VARIANT and a Nonossifying Desmoplastic Fibroma of the Mandible. [PDF]
Elena C+5 more
europepmc +1 more source
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones+6 more
wiley +1 more source
Multiple Endocrine Neoplasia Type 1 (MEN1) Syndrome Clinical Presentation and the Role of Newer Functional Imaging in the Diagnosis and Management: A Case Report. [PDF]
Singh R+4 more
europepmc +1 more source
Effects of Endocrine Disruptors on the Pituitary Gland.
Nariaki Fujimoto
openalex +2 more sources
Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB
Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang+9 more
wiley +1 more source
Importance of early detection in multiple endocrine neoplasia type 1: Clinical insights and future directions. [PDF]
Ren MJ+6 more
europepmc +1 more source
Schematic diagram of the mechanism of DEK regulating RhoA activation Ezrin. Upon house dust mite (HDM) stimulation, HDM‐specific immunoglobulin E (IgE) and inflammatory factors such as interleukin 4 (IL‐4), IL‐5, IL‐13, and eosinophils increased in the nasal mucosa.
Longzhu Dai+8 more
wiley +1 more source
Impact of exposure to a mixture of organophosphate esters on the adrenal glands of Sprague Dawley rats. [PDF]
Li Z, Hales BF, Robaire B.
europepmc +1 more source
The experimental type 2 diabetes model in rats induced by streptozotocin and nicotinamide showed that silver nanoparticles synthesized from lemongrass extract modulate blood glucose, water and food intake, and enhance antioxidant enzyme synthesis and weight gains.
Milad Faraji+6 more
wiley +1 more source