Results 221 to 230 of about 110,436 (285)

Evaluation of the effectiveness of near-infrared autofluorescence (NIRAF) imaging combined with immunocolloidal gold technique (ICGT) in identifying and protecting parathyroid glands during thyroid cancer surgery. [PDF]

Gland Surg
Tao W, Duan R, Gao Y, Wang J, Wang S, Hao J, Gao M.   +6 more
europepmc   +1 more source

ACE‐mediated Glycosylation Stabilizes PSAP To Promote GPR37‐dependent Macrophage‐Nucleus Pulposus Cells Crosstalk and TGFβ Signaling in Alleviating Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ACE can modulate the CBL‐mediated K48 ubiquitination degradation of PSAP by altering its glycosylation levels in NP cells. As a result, NP cells secrete PSAP, which interacts with GPR37 on macrophage surfaces, facilitating their polarization toward the M2 phenotype. These M2 macrophages subsequently secrete TGFβ, which exerts feedback effects on the NP
Youfeng Guo, Feng Wang, Bijun Wang, Yu Zhou, Chao Wang, Tao Hu, Desheng Wu   +6 more
wiley   +1 more source

An insulin-like peptide specific for a cockroach male reproductive gland. [PDF]

PLoS One
Pagone V, Pujal D, Maestro JL.
europepmc   +1 more source

SLC6A14 Drives Mitochondrial Fusion and Oxidative Phosphorylation to Promote Cancer Stemness and Early‐Onset of Breast Cancer

Advanced Science, EarlyView.
Elevated levels of the plasticizer DEHP associate with earlier breast cancer diagnosis. DEHP enhances glutamine‐powered energy production via the transporter SLC6A14 and pushes mitochondria toward fusion, driving tumor initiation by boosting cancer stemness. Blocking SLC6A14 lowers stemness, slows tumors, and improves chemotherapy response.
Dai‐Wei Hu, Chih‐Hao Huang, Yu‐Hao He, Ya‐Ling Wei, Shu‐Wei Hu, Fang‐Ju Cheng, Thanh Kieu Huynh, Bo‐Rong Chen, Bo‐Wei Wang, Li‐Chi Kuan, Der‐Yen Lee, Ming‐Hsin Yeh, Ya‐Jen Chang, Liang‐Chih Liu, Mien‐Chie Hung, Wei‐Chien Huang   +15 more
wiley   +1 more source

Structural and Hormonal Changes in Reproductive-Age Women Post-COVID-19: A Cross-Sectional Ultrasound and Biochemical Study. [PDF]

Diagnostics (Basel)
Yerkenova S, Lokshin V, Kurmanova A, Moiynbayeva S, Alikeyeva G, Kalibekova G, Abdirova T, Zhantenova Z, Shaikova K, Mireeva A, Turgumbayeva A.   +10 more
europepmc   +1 more source

Integrated Metabolic and Inflammatory Clustering Reveals Distinct Risk Profiles for Digestive Diseases

Advanced Science, EarlyView.
This study analyzes 398 432 participants, identifying four distinct metabolic‐inflammatory subtypes. These subtypes show a significant association with digestive disease risk. Cluster‐associated metabolite signatures partially explain this link. Machine learning models using these metabolites accurately predict risk for ten digestive diseases. Key risk
Zhenhe Jin, Qichen Chen, Liangfeng Zhou, Kexin Ye, Zhaoxue Liu, Wenxi Jiang, Linwen Luo, Yize Wang, Xiaohua Ye, Chaohui Yu, Zhe Shen   +10 more
wiley   +1 more source

Male accessory breast carcinoma: a rare case report and literature review. [PDF]

Front Oncol
Luo C, Wu S, Zhao S, Zeng Y.
europepmc   +1 more source

A Multifunctional Molecular Probe for Multimodal Imaging‐Guided Potent Photothermal/Photodynamic Therapy of Endometriosis

Advanced Science, EarlyView.
The cRGD‐ILD molecular probe integrates clinically available components: a cRGD peptide (integrin αvβ3 targeting), ICG (for fluorescence/photoacoustic imaging and phototherapy), and Gd‐DTPA (MRI contrast). Utilizing small size and receptor targeting, it achieves selective lesion accumulation.
Qiyu Zhong, Shuguang Yang, Xiao Li, Zhuang Jin, Jianyu Ma, Zhouzhou Liao, Jinbo Li, Bo Li, Xintao Shuai, Shuqin Chen   +9 more
wiley   +1 more source

Transcriptomics Guided Engineering of Exosome‐Encapsulated Bifunctional Nanosheets Targeting the Immune‐PI3K/Akt Axis for Osteoporosis Therapy

Advanced Science, EarlyView.
A multifunctional nanosheet–exosome hybrid system incorporating f‐CA(OH) nanosheets enriched with abundant surface vacancies are developed. These nanosheets fuse with natural exosomes, endowing them with nanozyme‐like catalytic capabilities while retaining their inherent biological functions.
Rongze Tang, Guanhong Liu, Congcong Wang, Minghao Chao, Guangyu Ma, Pengjin Wei, Siling Du, Junjie Li, Yufan Liu, Chaonan Jing, Guoquan Wu, Ming Guan, Hongliang Chen, Fenglei Gao   +13 more
wiley   +1 more source