Prokineticins (Endocrine Gland-Derived Vascular Endothelial Growth Factor and BV8) in the Bovine Ovary: Expression and Role as Mitogens and Survival Factors for Corpus Luteum-Derived Endothelial Cells [PDF]
Tatiana Kisliouk+5 more
openalex +1 more source
This study uncovers a novel mechanism in which p300‑catalyzed lactylation of HMGB1 triggers nuclear export of the HMGB1‐TIAR complex, driving TIAR‐dependent SGs formation in the cytoplasm. Mass spectrometry and mutagenesis reveals that K177 lactylation is essential for this export and subsequent SGs formation.
Chengyu Li+8 more
wiley +1 more source
Micro- and Nanoplastics as Disruptors of the Endocrine System-A Review of the Threats and Consequences Associated with Plastic Exposure. [PDF]
Tyc HJ+5 more
europepmc +1 more source
Estrogen action on the prostate gland: a critical mix of endocrine and paracrine signaling [PDF]
Gail P. Risbridger+2 more
openalex +1 more source
Targeting Hyperglycemic Bone Pre‐Metastatic Niche for Breast Cancer Bone Metastasis Therapy
This study reveals that breast cancer creates a hyperglycemic pre‐metastatic niche in bone prior to colonization and amplifies glucose metabolism post‐metastasis. To target this mechanism, a biomimetic enzyme‐engineered nanoplatform that disrupts tumor glycolytic pathways, proposing a therapeutic strategy to inhibit breast cancer bone metastasis by ...
Jianxin Ye+13 more
wiley +1 more source
Autoimmune Polyglandular Syndrome Type 3 and Overlapping Autoimmune Endocrinopathies: A Case Report. [PDF]
Nagarajan DR+2 more
europepmc +1 more source
Orthodontic relapse persists as a 120‐year challenge, as traditional retainers fail to remodel tissue, causing lifelong dependence. This study demonstrates a flexible magnetoelectric retainer (FMOR) enabling wireless periodontal remodeling. FMOR cues shift periodontal ligament cell (PDLC) paracrine signaling, promoting M2 macrophages, osteogenic ...
Haoqi Lei+9 more
wiley +1 more source
An insulin-like peptide specific for a cockroach male reproductive gland. [PDF]
Pagone V, Pujal D, Maestro JL.
europepmc +1 more source
Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene
Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan+15 more
wiley +1 more source
Propolis mitigates histopathological alterations in the pituitary gland and reproductive system of female albino rats subjected to cadmium toxicity. [PDF]
Albishtue AA+3 more
europepmc +1 more source