Results 261 to 270 of about 801,043 (361)

Progress report on multiple endocrine neoplasia type 1. [PDF]

Fam Cancer
Halperin R, Tirosh A.
europepmc   +1 more source

Selection of DNA Aptamers Against Parathyroid Hormone for Electrochemical Impedimetric Biosensor System Development

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT This work presents the pioneering development of an aptamer‐based electrochemical biosensor for real‐time monitoring of parathyroid hormone (PTH) levels, with a focus on intraoperative assessment during parathyroid surgery. It introduces, for the first time, the selection and characterization of aptamers targeting distinct segments of the PTH ...
Reza Didarian, Saharnaz Bargh, Almina Gülerman, Veli Cengiz Özalp, Özcan Erel, Nimet Yildirim‐Tirgil   +5 more
wiley   +1 more source

Hormone circuit explains why most HPA drugs fail for mood disorders and predicts the few that work. [PDF]

Mol Syst Biol
Milo T, Nir Halber S, Raz M, Danan D, Mayo A, Alon U.   +5 more
europepmc   +1 more source

Oral paltusotine, a nonpeptide selective somatostatin receptor 2 agonist: Mass balance, absolute bioavailability and metabolism in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Paltusotine is a novel, nonpeptide, selective somatostatin receptor 2 agonist in development for the treatment of acromegaly and carcinoid syndrome. This study investigated the mass balance, routes of excretion, absolute bioavailability and metabolite profile of orally administered paltusotine.
Rosa Luo, Ajay Madan, Christine T. Ferrara‐Cook, Deepak Dalvie, Lance Goulet, R. Scott Struthers, Alan S. Krasner   +6 more
wiley   +1 more source

Unexplained Hypokalemia in a Patient With Obesity Harboring an Armadillo Repeat-Containing 5 (ARMC5) Gene Variant: A Case Report. [PDF]

Cureus
Taguchi A, Uraki S, Akiyama M, Nagao Y, Watanabe K, Mizukami Y, Ohta Y.   +6 more
europepmc   +1 more source

Pharmacokinetics of betamethasone in pre‐eclampsia: An in vivo and ex vivo study

British Journal of Clinical Pharmacology, EarlyView.
Aims To enhance understanding of betamethasone and its metabolites' pharmacokinetics in pregnancy, specifically early‐onset pre‐eclampsia, through a population pharmacokinetic model. Additionally, to investigate the placental metabolism and transfer of betamethasone and its main metabolites.
Sam Schoenmakers, Letao Li, Anna C. M. Kluivers, Michelle Broekhuizen, Madhavi S. Harhangi, A. H. Jan Danser, Irwin Reiss, Karel Allegaert, Sjoerd A. A. van den Berg, Bertrand D. van Zelst, Ron H. N. van Schaik, Philip L. J. DeKoninck, Emma Ronde, Sebastiaan D. T. Sassen, Sinno H. P. Simons, Birgit C. P. Koch   +15 more
wiley   +1 more source

The Role of Adenogenesis Factors in the Pathogenesis of Endometriosis. [PDF]

Int J Mol Sci
Signorile PG, Baldi A, Viceconte R, Boccellino M.   +3 more
europepmc   +1 more source

The Known and Unknown About Female Reproductive Tract Mucus Rheological Properties

BioEssays, EarlyView.
Mucus viscosity changes as spermatozoa travel through the female reproductive tract to the egg in humans, bovines, mice, and other mammals. These changes may aid in spermatozoa navigation. However, limited information is available on the viscoelastic properties of female reproductive tract mucus, and consistent measurement techniques are lacking ...
Luke Achinger, Derek F. Kluczynski, Abigail Gladwell, Holly Heck, Faith Zhang, Ethan Good, Alexis Waggoner, Mykala Reinhart, Megan Good, Dawson Moore, Dennis Filatoff, Supriya Dhar, Elisa Nigro, Lucas Flanagan, Sunny Yadav, Trinity Williams, Aniruddha Ray, Tariq A. Shah, Matthew W. Liberatore, Tomer Avidor‐Reiss   +19 more
wiley   +1 more source

A Novel Multiple Endocrine Neoplasia Type 1 Gene Variant Found in Scalp Pulmonary Neuroendocrine Tumor Metastasis. [PDF]

JCEM Case Rep
Takahashi Y, Horikawa Y, Matsuyama Y, Asai K, Endo J, Yabe D.   +5 more
europepmc   +1 more source

Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells remain the industry standard for producing numerous therapeutic proteins, particularly monoclonal antibodies (mAbs). However, achieving higher recombinant protein titers remains an ongoing challenge and a fundamental understanding of the cellular mechanism driving improved bioprocess performance remains ...
Kate E. Meeson, Joanne Watson, Susan Rosser, Ellie Hawke, Andrew Pitt, Tessa Moses, Leon Pybus, Magnus Rattray, Alan J. Dickson, Jean‐Marc Schwartz   +9 more
wiley   +1 more source