Advanced Science, EarlyView.During sepsis, pulmonary vascular endothelial cells secrete chemokine CCL7, which plays a pivotal role in facilitating the infiltration of C‐C motif chemokine receptor 1‐positive (CCR1+) macrophages into lung tissue. Activation of the CCL7–CCR1 axis enhances the succinylation of STAT1 mediated by KAT2A, thereby driving metabolic reprogramming and ...
Xue Li +5 more
wiley +1 more source
Clinical evaluation of determinations of free and serum protein bound triiodthyronine (dextran gel filtration) [PDF]
, 1965 Heinze, H. G. +3 more
core
Advanced Science, EarlyView.This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer +8 more
wiley +1 more source
The orca (<i>Orcinus orca</i>) pituitary gland: an anatomical, immunohistochemical and ultrastructural analysis. [PDF]
Front NeuroanatAlonso-Almorox P +6 more
europepmc +1 more source
Effects of Endocrine Disruptors on the Pituitary Gland.
, 2001 Nariaki Fujimoto
openalex +2 more sources
Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep
Advanced Science, EarlyView.The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu +12 more
wiley +1 more source
Balancing hormonal symphony: the dynamics of reproduction and pregnancy. [PDF]
BMC Endocr DisordDrakopoulos P.
europepmc +1 more source
Peptide Hormone‐Mediated Regulation of Plant Development and Environmental Adaptability
Advanced Science, EarlyView.In this review, recent advances in understanding the roles of plant peptide hormones in regulating growth, reproduction, and environmental adaptability are systematically summarized. It further elucidates the challenges in studying these peptides, such as their low abundance, functional redundancy, and complex signaling mechanisms, and highlights their
Xin Li +8 more
wiley +1 more source
The role of thymectomy during parathyroidectomy in multiple endocrine neoplasia type 1-associated hyperparathyroidism: a systematic review and meta-analysis. [PDF]
World J Surg OncolToraih EA +10 more
europepmc +1 more source
Spatiotemporal Adaptations‐Driven Dynamic Thra Activation Simulates a Skin Wound Healing Response
Advanced Science, EarlyView.This study uncovers the thyroid hormone receptor Thra as a pivotal regulator that spatiotemporally orchestrates dual‐phase skin repair. Epidermal Thra accelerates barrier restoration via glutathione‐driven keratin assembly, while dermal Thra establishes angiogenic niches through SAA3‐FN1‐mediated matrix remodeling.
Zeming Li +15 more
wiley +1 more source