Results 51 to 60 of about 875,014 (369)

Cancer of the parathyroid glands [PDF]

open access: yesPraxis Medica, 2016
Parathyroid glands are small endocrine gland in the neck that men secrete parathyroid hormone , or PTH ( PTH) , which together with calcitonin and vitamin - D has a primary role in regulating the concentration of calcium and phosphate in the body.
Odalović Božidar   +6 more
doaj   +1 more source

Pediatric thyroid disease: when is surgery necessary, and who should be operating on our children? [PDF]

open access: yes, 2013
Surgical diseases of the thyroid in the pediatric population represent a diverse set of both benign and malignant conditions. Overall, incidence is rare.
Breuer, Christopher   +3 more
core   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

Topographic Reorganization of Cerebrovascular Mural Cells under Seizure Conditions

open access: yesCell Reports, 2018
Summary: Reorganization of the neurovascular unit has been suggested in the epileptic brain, although the dynamics and functional significance remain unclear.
Margarita Arango-Lievano   +8 more
doaj   +1 more source

Hyperthyroidism in cats, part I : anatomy, physiology, pathophysiology, diagnosis and imaging [PDF]

open access: yes, 2016
In the first part of this review article, thyroid anatomy, physiology and pathophysiology are reviewed to continue more specifically on hyperthyroidism, the most common thyroid disorder in cats.
Daminet, Sylvie   +4 more
core   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

open access: yesFEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis   +3 more
wiley   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Persons Versus Brains: Biological Intelligence in Human Organisms [PDF]

open access: yes, 2001
I go deep into the biology of the human organism to argue that the psychological features and functions of persons are realized by cellular and molecular parallel distributed processing networks dispersed throughout the whole body.
Steinhart, E.
core  

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