Results 251 to 260 of about 427,887 (351)
Approach to the Patient with Affection and Disease of the Endocrine System
M. Yabluchansky +5 more
openalex +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
The impact of long-term low-dose ionizing radiation on human health: risks and protective measures. [PDF]
Zhang Y +8 more
europepmc +1 more source
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang +3 more
wiley +1 more source
A rare case of POEMS syndrome with unique endoscopic presentation. [PDF]
Zhou JK +6 more
europepmc +1 more source
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang +7 more
wiley +1 more source
Fibroblast growth factor 23: Regulation, signalling and systemic links between bone, metabolism and inflammation. [PDF]
Crespo-Golmar A +9 more
europepmc +1 more source

