Results 211 to 220 of about 477,437 (308)

Preliminary evidence of improved liver biomarkers in adolescents with obesity and suspected metabolic dysfunction‐associated steatotic liver disease treated with semaglutide: A case series

open access: yesJPGN Reports, EarlyView.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects 30%–40% of youth with obesity and lacks approved pharmacologic therapies. In this single‐center retrospective case series at a tertiary care safety‐net children's hospital, we evaluated five adolescents (mean age: 17.0 years; 100% Hispanic; 60% male; mean body mass index:
Rachel Schenker   +3 more
wiley   +1 more source

Muscle Ultrasound Echo Intensity Detects Insulin Resistance Before Changes in HbA1c or Fasting Glucose, Independent of BMI

open access: yesJournal of Ultrasound in Medicine, EarlyView.
Objectives To quantify the association between skeletal muscle echo intensity (MEI), measured by ultrasound, and clinical markers of insulin resistance and glycemic control, and evaluate MEI's diagnostic accuracy in identifying insulin resistance. Methods In this cross‐sectional study, 20 adults with obesity (mean body mass index [BMI] 34.4 ± 2.6 kg/m2,
Steven B. Soliman   +8 more
wiley   +1 more source

Vitexin Attenuates the Growth and Glycolysis of Acute Myeloid Leukemia Cells by Suppressing the HIF‐1α‐Modulated YAP Pathway Under Hypoxic Conditions

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Vitexin, an apigenin flavone glycoside, exhibits antitumor activity against various cancers including leukemia. Hypoxia enhances glycolysis, thereby promoting tumor growth. In this study, we aimed to explore the effects of vitexin on hypoxia‐induced growth and glycolysis in acute myeloid leukemia (AML) cells and determine the underlying ...
Ping Wang   +4 more
wiley   +1 more source

Improving Medical‐Dental Integration Through Inter‐Provincial, Inter‐Professional Collaboration

open access: yes
Journal of Dental Education, EarlyView.
Ishita Patel   +3 more
wiley   +1 more source

Alogliptin Reduces Oxidative Stress in Cardiomyocytes and Ameliorates Diabetic Cardiomyopathy via the AURKB/NLGN2 Signaling

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cardiomyopathy (DCM) is a common complication of diabetes mellitus. This study investigated the effects of alogliptin on DCM and its underlying mechanisms. A DCM model was constructed and treated with alogliptin. Downstream targets of alogliptin were screened using bioinformatics analysis.
Li‐Jing Jiao   +7 more
wiley   +1 more source

Bilateral primary adrenal lymphoma

open access: yesJournal of General and Family Medicine
Rio Shimizu, Shogo Shirota
doaj   +1 more source

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