Results 41 to 50 of about 477,437 (308)

Grid infrastructures supporting paediatric endocrinology across Europe [PDF]

open access: yes, 2007
Paediatric endocrinology is a highly specialised area of clinical medicine with many experts with specific knowledge distributed over a wide geographical area.
Ajayi, O., Sinnott, R.O., Stell, A.J.
core   +2 more sources

Functional Integration of Different‐Sex Gonad Transplants Into the Adult Mouse Hypothalamic Pituitary Gonadal Axis

open access: yesAdvanced Biology, EarlyView.
This study introduces and investigates different‐sex gonad transplants in a mouse model of gender‐affirming hormone therapy. Ovaries and testes implanted into gonadectomized adults exhibit gametogenesis and steroidogenesis independent of the sex of the host.
Daniel R. Pfau   +8 more
wiley   +1 more source

Reproductive tract biology: Of mice and men. [PDF]

open access: yes, 2019
The study of male and female reproductive tract development requires expertise in two separate disciplines, developmental biology and endocrinology.
Baskin, Laurence S   +5 more
core  

Increased expression of circulating miRNA-93 in women with polycystic ovary syndrome may represent a novel, non-invasive biomarker for diagnosis [PDF]

open access: yes, 2015
MicroRNAs (miRNA) are a novel class of small noncoding single-stranded RNA molecules that regulate gene expression. There is increasing evidence of their importance in polycystic ovary syndrome (PCOS). The objective was to determine if miRNA-93 and miRNA-
Atkin, S. L.   +3 more
core   +1 more source

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

open access: yesAdvanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma   +11 more
wiley   +1 more source

CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride Turnover

open access: yesAdvanced Science, EarlyView.
This study identifies CIDEC, an lipid droplet (LD)‐fusion associated protein upregulated by CREBH during early regeneration, as a negative regulator of liver regeneration through its unexpected role in sequestering triglyceride (TG) within LDs. CIDEC depletion reduces LD size, mobilizes LD‐stored TG, enhances TG catabolism and free fatty acid (FFA ...
Feng Ouyang   +16 more
wiley   +1 more source

Use of interactive “Case Study” method in the training of future physicians

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2019
Last decade is characterized by rapid use of a large number of virtual technologies in the different spheres of human activity. Introduction of innovative technologies into education processes in the system of higher education is an actual problem of its
I.V. Cherniavska   +3 more
doaj   +1 more source

Leptin receptor in the chicken ovary: potential involvement in ovarian dysfunction of ad libitum-fed broiler breeder hens [PDF]

open access: yes, 2004
In hens, the ovarian follicles committed to ovulation are arranged in an ordered follicular hierarchy. In standard broiler breeders hens genetically selected for high growth rate the reproductive function is clearly dysfunctional.
Cassy, Sandrine   +5 more
core   +3 more sources

Impact of Intended Isocaloric Early versus Late Time‐Restricted Eating on Plasma Lipidome in Women with Overweight or Obesity: Secondary Analysis of the ChronoFast Trial

open access: yesAdvanced Science, EarlyView.
Women with overweight or obesity follow intended isocaloric early and late time‐restricted eating (TRE) in a crossover trial. Shotgun plasma lipidomics reveals no significant differences between interventions, but identify pronounced lipid changes—including reductions in ceramides and phosphatidylcholines—within the early TRE.
Kristof Szekely   +15 more
wiley   +1 more source

Carbachol increases intracellular free calcium concentrations in human granulosa-lutein cells [PDF]

open access: yes, 1992
We investigated whether the stimulation of human granulosa-lutein cells with muscarinic and nicotinic receptor agonists can cause increases in intracellular free calcium (Ca2+), using Fura-2 microfluorimetry.
Föhr, K. J.   +3 more
core   +1 more source

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