Results 91 to 100 of about 1,477,498 (302)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Prognostic analysis of 2-5 cm diameter gastric stromal tumors with exogenous or endogenous growth. [PDF]

open access: yesWorld J Surg Oncol, 2023
Lin C   +7 more
europepmc   +1 more source

Endogenous Versus Exogenous Growth Facing a Fertility Shock [PDF]

open access: yes
This paper simulates the impact of a permanent fertility shock on economic growth, using endogenous versus exogenous growth OLG models. An endogenous growth model, with education as the engine of growth, dampens the negative impact of a decline in ...
Medeiros, João
core  

Knowledge, consumption, and endogenous growth [PDF]

open access: yesJournal of Evolutionary Economics, 2000
Formal theories of economic growth, including newly popular models of "endogenous" growth, rely on a conception of knowledge as explicit and costlessly transferable. Once created, knowledge can spill easily into the hands of others at zero marginal cost, a process of "spillover" that is the source of the increasing returns that generate economic growth.
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Alternative implications of increasing corruption for endogenous growth [PDF]

open access: yesStrategic Management, 2015
The paper discusses the effect of corruption upon economic growth in the neoclassical framework. It is shown that increasing corruption and decreasing taxation shift the growth path in the same direction and this direction depends on the difference ...
István Bessenyei
doaj  

Population aging and endogenous economic growth [PDF]

open access: yes
This article investigates the consequences of population aging for long-run economic growth perspectives. We introduce age specific heterogeneity of households into a model of research and development (R&D) based technological change.
Klaus Prettner
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Semi-endogenous growth when population is decreasing [PDF]

open access: yes
The paper analyzes the effect of a negative population growth rate on per capita income growth using a simple model of semi-endogenous growth. It is shown that there is a non-monotonous relationship between population growth rates and long-run per capita
Thomas Christiaans
core  

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