Results 131 to 140 of about 1,383,614 (360)
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim+11 more
wiley +1 more source
Sectoral Convergence in Output Per Worker Between Portuguese Regions [PDF]
The aim of this paper is to present a further contribution to the analysis of absolute convergence (and), associated with the neoclassical theory, and conditional, associated with endogenous growth theory, of the sectoral productivity at regional level.
arxiv
Gifts, Bequests and Growth [PDF]
A familiar result in the theory of private intergenerational transfers is that competitive equilibria with gifts from children to their parents are dynamically inefficient whereas they are dynamically efficient with bequests from parents to their ...
Berthold U. Wigger
core
Light‐Activatable Hyaluronic Acid‐Derivatives Releasing Nitric Oxide and Their Delivery in the Skin
This work explores the development of photoactivatable hyaluronic acid (HA) derivatives functionalized with nitric oxide (NO) photodonors for light‐controlled therapeutic applications. The HA derivatives demonstrate enhanced keratinocyte proliferation and migration, effective NO release, and skin penetration when formulated as microemulsions.
Giuseppe Longobardi+7 more
wiley +1 more source
Mathematical control theory, the immune system, and cancer [PDF]
Simple ideas, endowed from the mathematical theory of control, are used in order to analyze in general grounds the human immune system. The general principles are minimization of the pathogen load and economy of resources. They should constrain the parameters describing the immune system. In the simplest linear model, for example, where the response is
arxiv
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley +1 more source
In the Central-Eastern Europe countries a policy of regional development was not present until a territorial reform (that is dividing country into regions: Poland 1999, Slovakia 2002, Czech Republic 2000) related to the accession of these countries into ...
Piotr Pachura+2 more
doaj
Identifying the active flow regions that drive linear and nonlinear instabilities [PDF]
A new framework for the analysis of unstable oscillator flows is explored. In linear settings, temporally growing perturbations in a non-parallel flow represent unstable eigenmodes of the linear flow operator. In nonlinear settings, self-sustained periodic oscillations of finite amplitude are commonly described as nonlinear global modes.
arxiv
Population and Ideas: A Theory of Endogenous Growth [PDF]
Charles I. Jones
openalex +1 more source
Efficiency, Depth and Growth: Quantitative Implications of Finance and Growth Theory [PDF]
We develop a parsimonious finance and endogenous growth model with microeconomic frictions in entrepreneurship and a role for credit constraints. We demonstrate that though an efficiency-growth relation will always exist, the efficiency-depth-growth ...
Alex Trew
core