Results 191 to 200 of about 1,383,614 (360)

Muscle‐Derived Small Extracellular Vesicles Mediate Exercise‐Induced Cognitive Protection in Chronic Cerebral Hypoperfusion

Advanced Science, EarlyView.
sEVs have a critical role in orchestrating interorgan crosstalk and mediating exercise‐induced therapeutic effects. Lin et al. demonstrates that sEVs miR‐17/20a‐5p mediates the muscle‐brain crosstalk and emphasizes the central role of mTOR signaling in executing molecular programs that can protect brain health in response to exercise. Abstract Physical
Huawei Lin, Lianhua Yin, Weilin Liu, Rui Li, Tao Jiang, Minguang Yang, Yajun Cao, Sinuo Wang, Yan Yu, Cong Chen, Xiaoqin Guo, Wenju Wang, Huanhuan Liu, Yaling Dai, Jiamin Yan, Yanting Lin, Yanyi Ding, Chendong Ruan, Lei Yang, Tiecheng Wu, Jing Tao, Lidan Chen   +21 more
wiley   +1 more source

Growth, Development, and Technological Change [PDF]

The theory of endogenous technical change has deeply contributed to our understanding of the fundamental sources of economic growth and development. In this chapter we survey important contributions in the field by focussing on the basic structure of ...
Thomas Steger, Volker Grossmann
core  

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

Semi-endogenous or fully endogenous growth? A unified theory

, 2023
Guido Cozzi
openalex   +1 more source

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

Advanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare, Kshama Kundu, Papiya Dey, Krupa Thankam Philip, Nitish Chauhan, Muskan Sharma, Sankarsingh Kesharsingh Rajput, Birija Sankar Patro   +7 more
wiley   +1 more source

The effect of H₂O₂ on elongation growth and oxidative stress in maize coleoptile cells treated with auxin and fusicoccin. [PDF]

Sci Rep
Siemieniuk A, Rudnicka M, Karcz W.
europepmc   +1 more source

Money Velocity in an Endogenous Growth Business Cycle with Credit Shocks [PDF]

The explanation of velocity has been based in substitution and income effects, since Keynes’s (1923) interest rate explanation and Friedman’s (1956) application of the permanent income hypothesis to money demand.
Max Gillman, Michal Kejak, Szilárd Benk
core  

HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou, Yan Guo, Shuang Xu, Mi Bai, Weidong Cao, Yue Zhang, Zhanjun Jia, Aihua Zhang   +7 more
wiley   +1 more source

Shin Ihda's "manifestation model of mood disorders" based on situation theory and twin studies. [PDF]

PCN Rep
Echizen K, Ohmae S.
europepmc   +1 more source

The GhWL1‐GhH1‐GhGA2OX1 Transcriptional Module Regulates Cotton Leaf Morphology

Advanced Science, EarlyView.
This study identified GhWL1 as a key gene involved in regulating leaf development through analysis of a T‐DNA insertion mutant. The GhWL1‐GhH1 complex is shown to positively regulate GhGA2OX1 by directly binding to its promoter, thereby establishing the GhWL1‐GhH1‐GhGA2OX1 module as a critical pathway in leaf development.
Jingjing Zhan, Xiaoshuang Zhang, Ye Wang, Hang Zhao, Yu Chu, Peng Wang, Yanli Chen, Xi Wei, Wenqiang Qin, Menghan Liu, Jie Kong, Fuguang Li, Xiaoyang Ge   +12 more
wiley   +1 more source