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A Transmissible Human Endogenous Retrovirus [PDF]
AIDS Research and Human Retroviruses, 2002 The transmissibility of the human endogenous retrovirus HERV-H/RGH-2 was investigated by marker rescue: intraspecies transmission of HERV-H/RGH-2 retrovirus particles was attempted by cocultivation of virion-producing, long-term cell cultures spontaneously formed from peripheral blood mononuclear cells from several multiple sclerosis patient cultures ...
Christensen, T. +3 more
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Detection of porcine endogenous retrovirus in xenotransplantation
Reproductive Biology, 2014Xenotransplantation can provide a virtually limitless supply of cells, tissues and organs for a variety of therapeutic procedures. Cells and tissues for use in human transplantation procedures could be supplied using material taken from pigs. However, there is a potential risk of transmission of porcine infectious agents, including porcine endogenous ...
Joanna Gola, Urszula Mazurek
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Cellular and Molecular Life Sciences, 2008
Although endogenous retroviruses are ubiquitous features of all mammalian genomes, the process of initial germ line invasion and subsequent inactivation from a pathogenic element has not yet been observed in a wild species. Koala retrovirus (KoRV) provides a unique opportunity to study this process of endogenisation in action as it still appears to be ...
Tarlinton, Rachael Eugenie +2 more
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Although endogenous retroviruses are ubiquitous features of all mammalian genomes, the process of initial germ line invasion and subsequent inactivation from a pathogenic element has not yet been observed in a wild species. Koala retrovirus (KoRV) provides a unique opportunity to study this process of endogenisation in action as it still appears to be ...
Tarlinton, Rachael Eugenie +2 more
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Transfection by exogenous and endogenous murine retrovirus DNAs [PDF]
Cell, 1979 Abstract We have used DNA transfection to study the endogenous retrovirus genomes inherited by uninfected mouse cells. Quantitative assays for infectious DNAs of ecotropic and xenotropic murine leukemia viruses (MuLVs) were developed using donor DNAs of cells that were exogenously infected with ecotropic Moloney, AKR or BALB MuLVs, or with xenotropic ...
Copeland, N G, Cooper, G M
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Endogenous retrovirus expression in testis and epididymis
Biochemical Society Transactions, 2007ERVs (endogenous retroviruses), which comprise 8–10% of mouse and human genomes, are present in thousands of copies, ranging in size from complete 9 kb virus to truncated partial sequences. Despite well-documented differential expression of ERVs in normal and diseased tissues, their biological significance remains controversial. Work in this laboratory
R.C. Crowell, A.A. Kiessling
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Porcine endogenous retrovirus – advances, issues and solutions
Xenotransplantation, 2002No abstract.
Gary Quinn, Linda Scobie, Clive Patience
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Porcine endogenous retrovirus and other viruses in xenotransplantation
Current Opinion in Organ Transplantation, 2009Potential transmission of zoonotic porcine viruses is a major safety issue in xenotransplantation. This review will first summarize recent studies involving transmission and control of the major concern, porcine endogenous retrovirus (PERV). Second, the potential for zoonotic transfer and safety measures required against other viruses of concern will ...
Yasuhiro Takeuchi, Linda Scobie
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Organization of Endogenous Retrovirus Genes
1980In mammals virogenes are multiple copy elements. Estimates of the number of copies lie between five and several hundred. This wide range results from variations in the copy number of different virogenes and from technieal considerations. The conventional means for determining the number of copies of a particular gene in mammalian DNA is to follow the ...
David R. Strayer, David Gillespie
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Endogenous Retroviruses Related to Jaagsiekte Sheep Retrovirus
2003Ovine betaretroviruses consist of exogenous viruses [jaagsiekte sheep retrovirus (JSRV) and enzootic nasal tumor virus, (ENTV)] associated with neoplastic diseases of the respiratory tract and 15-20 endogenous viruses (enJSRV) stably integrated in the ovine and caprine genome. Phylogenetic analysis of this group of retroviruses suggests that the enJSRV
Demartini, J.C. +4 more
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Endogenous Retrovirus-K and Nervous System Diseases
Current Neurology and Neuroscience Reports, 2014A new appreciation of the microbiome is changing the way we perceive human health and disease. The holobiontic nature of humans is even etched into our DNA in the form of viral symbionts. Empirical evidence for the presence of endogenous retroviruses (ERVs) in the human genome and their activity in homeostatic and pathologic states has accumulated ...
Renée N. Douville +2 more
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