Meniere's disease: Structural considerations in early cochlea hydrops
The structural features of the human cochlea are projected to determine the sequential vulnerability to endolymphatic hydrops in the several cochlea turns. Abstract Objective Structural features of the human cochlea may control early lesion formation in endolymphatic hydrops.
Daniel J. Pender
wiley +1 more source
Review: Morphological Changes Associated with Endolymphatic Hydrops [PDF]
Endolymphatic hydrops of the inner ear is identified as a swelling of the endolymphatic spaces. This morphopathology in man can only be confirmed at postmortem examination although it is believed to underlie the auditory dysfunction and vestibular ...
Horner, K. C.
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Treatment of peripheral vestibular vertigo, such as intratympanic gentamicin, usually leads to serious complications such as hearing loss due to the lack of specificity on the vestibular hair cell injury. In this article, the authors developed a PDT‐based method to precisely injure the vestibular hair cells.
Yingkun Yang+5 more
wiley +1 more source
A Comparison of Distortion Product Otoacoustic Emission Properties in Meniere's Disease Patients and Normal-Hearing Participants [PDF]
Objectives: Postmortem examination of temporal bones of Meniere's disease patients consistently show dilated endolymphatic spaces of the inner ear, for which the term endolymphatic hydrops has been coined.
Abel+49 more
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Multiomic‐based immune response profiling in migraine, vestibular migraine and Meniere's disease
Migraine (MI) and vestibular migraine (VM) show no difference in their immune transcriptome. Type 1 innate immune cells polarise NK cells to cytotoxic NK‐e via the release of interleukin (IL)‐2, IL‐12, IL‐15 and IL‐18 in the MI cluster. Besides, scRNAseq data define two Meniere's disease (MD) cluster, one inactive and one driven by monocytes. Stem cell
Pablo Cruz‐Granados+9 more
wiley +1 more source
Four‐hour‐delayed 3D‐FLAIR MRIs in patients with acute unilateral peripheral vestibulopathy
Abstract Objective Conventionally, MRI aids in differentiating acute unilateral peripheral vestibulopathy/vestibular neuritis (AUPV/VN) from mimickers. Meanwhile, the diagnostic utility of MRIs dedicated to the inner ear remains to be elucidated for diagnosing AUPV/VN. Methods We prospectively recruited 53 patients with AUPV/VN (mean age ± SD = 60 ± 15
Keun‐Tae Kim+6 more
wiley +1 more source
Tone Burst Electrocochleography for the Diagnosis of Clinically Certain Meniere's Disease
The technique of transtympanic electrocochleography was initially developed as an objective hearing threshold test by Eggermont. Gibson et al. (1977) claimed that an enlarged direct current component of the action potential (AP) called the summating ...
Jeremy Hornibrook
doaj +1 more source
Imaging of endolymphatic hydrops on a vertigo attack of Meniere’s disease [PDF]
Meniere’s disease (MD) characteristically presents with endolymphatic hydrops (EH), which can be visualized with gadolinium-enhanced inner ear magnetic resonance imaging (MRI).
Naganawa, Shinji+5 more
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Hearing, balance, and imaging assessment in adolescent Menière's disease: A retrospective analysis
Adolescent with Menière's disease (MD) have similar vestibular information inputs with that of recurrent vertigo of childhood, but the ability for the nerve center to use these clues to maintain balance is worse in pediatric MD. There were potential differences in vestibular weights in children with unilateral and bilateral MD, also potential effects ...
Xiaofei Li+11 more
wiley +1 more source
The Vestibular Epithelia in Experimental Hydrops [PDF]
Morpho-pathological features, observed by scanning electron microscopy, in guinea pigs with endolymphatic hydrops of 4-14 months included shortening of the hair cell tufts, loss of tufts, retraction of sensory hair cells away from the surrounding tissue ...
Horner, K. C., Rydmarker, S.
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