Results 41 to 50 of about 4,003 (175)

Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter? [PDF]

open access: yesPLoS ONE, 2018
INTRODUCTION:Middle ear application of gentamicin is a common medical treatment for uncontrolled Ménière's disease. The objective of the study was to evaluate the impact of endolymphatic hydrops on inner ear delivery.
Pedro Marques   +3 more
doaj   +1 more source

SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice.

open access: yesPLoS Genetics, 2013
Mutations of SLC26A4 are a common cause of human hearing loss associated with enlargement of the vestibular aqueduct. SLC26A4 encodes pendrin, an anion exchanger expressed in a variety of epithelial cells in the cochlea, the vestibular labyrinth and the ...
Xiangming Li   +13 more
doaj   +1 more source

Results of surgical treatment of patients with Meniere’s disease

open access: yesМедицинский совет, 2019
The study analyzed the clinical effect of the surgical treatment of 25 patients with Meniere’s disease, 20 of which underwent endolymphatic sac drainage and five of which underwent vestibular neurectomy via translabyrinthine approach.
V. M. Svistushkin   +4 more
doaj   +1 more source

What a Neurosurgeon Should Know About the Endolymphatic Sac: Part 3 – Ménière Disease

open access: yesBrazilian Neurosurgery, 2023
Objective To elucidate all the aspects that neurosurgeons should know about the Ménière disease (MD). Methods Review of guidelines, books, and studies from 1933 to 2021, from basic to translational research, using human and animal ...
Marco Antônio Schlindwein Vaz   +8 more
doaj   +1 more source

Radiological Configuration of the Vestibular Aqueduct Predicts Bilateral Progression in Meniere's Disease

open access: yesFrontiers in Neurology, 2021
Objective: Meniere's disease (MD) progresses from unilateral to bilateral disease in up to 50% of patients, often chronically and severely impairing balance and hearing functions.
David Bächinger   +6 more
doaj   +1 more source

Hearing Outcomes Following Endolymphatic Duct Blockage Surgery and Factors Associated with Improved Audition at Two Years Follow-Up

open access: yesAudiology Research, 2023
Objective: To evaluate hearing outcomes at 2 years post endolymphatic duct blockage (EDB) surgery, with an analysis of factors that may predict hearing improvement. Study Design: Retrospective comparative study. Setting: Tertiary care center.
Issam Saliba, Marc-Henri Asmar
doaj   +1 more source

Calcium functional imaging with high-resolution CT in the inner ear

open access: yesScientific Reports, 2021
Although the otolith and otolith organs correlate with vertigo and instability, there is no method to investigate them without harmful procedures. We will create the technique for 3D microanatomical images of them, and investigate the in vivo internal ...
Hisaya Tanioka, Sayaka Tanioka
doaj   +1 more source

A Historical Perspective on Surgical Manipulation of the Membranous Labyrinth for Treatment of Meniere's Disease

open access: yesFrontiers in Neurology, 2021
Meniere's disease is an inner ear disorder without a known cause. Endolymphatic hydrops is a swelling of the endolymph spaces that has been observed consistently on post-mortem histology in patients with a history of Meniere's disease but can occur in ...
Calvin J. Kersbergen, Bryan K. Ward
doaj   +1 more source

What a Neurosurgeon Should Know about the Endolymphatic Sac: Part 1–Anatomy and Physiology

open access: yesBrazilian Neurosurgery
Objective To describe the microsurgical anatomy and the physiology of the endolymphatic sac (ES) that a neurosurgeon should know.
Marco Antônio Schlindwein Vaz   +10 more
doaj   +1 more source

Endolymphatic sac tumour in von Hippel-Lindau disease: management strategies [PDF]

open access: yesActa Otorhinolaryngologica Italica, 2017
Il carcinoma del sacco endolinfatico è un tumore molto raro come evidente dai dati presenti in letteratura ove anche centri di esperienza riferiscono tuttavia casistiche limitate.
E. Zanoletti   +5 more
doaj   +1 more source

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