Results 71 to 80 of about 140,758 (271)

A comprehensive embryonic staging series of the turtle Trachemys scripta

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Turtles hold a unique place in vertebrate evolutionary history, making them critical assets in embryology research. Yet, they remain understudied as potential model organisms in the field. Here, to support experimental manipulations with turtle embryos, we have created a complete normal table of development for comprehensive ...
Christina M. Noravian   +6 more
wiley   +1 more source

SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice.

open access: yesPLoS Genetics, 2013
Mutations of SLC26A4 are a common cause of human hearing loss associated with enlargement of the vestibular aqueduct. SLC26A4 encodes pendrin, an anion exchanger expressed in a variety of epithelial cells in the cochlea, the vestibular labyrinth and the ...
Xiangming Li   +13 more
doaj   +1 more source

Developmental Expression of Membrane Pumps and Ion Channels in Human Vestibular Endolymph Homeostasis

open access: yesDevelopmental Neurobiology, Volume 86, Issue 1, January 2026.
ABSTRACT The expression patterns of key membrane pumps and ion channels involved in endolymph cycling have been studied in the rodent inner ear and the developing and adult human cochlea. However, little is known about their expression during the development of the human vestibular system.
Edward S. A. van Beelen   +4 more
wiley   +1 more source

Results of surgical treatment of patients with Meniere’s disease

open access: yesМедицинский совет, 2019
The study analyzed the clinical effect of the surgical treatment of 25 patients with Meniere’s disease, 20 of which underwent endolymphatic sac drainage and five of which underwent vestibular neurectomy via translabyrinthine approach.
V. M. Svistushkin   +4 more
doaj   +1 more source

What a Neurosurgeon Should Know About the Endolymphatic Sac: Part 3 – Ménière Disease

open access: yesBrazilian Neurosurgery, 2023
Objective To elucidate all the aspects that neurosurgeons should know about the Ménière disease (MD). Methods Review of guidelines, books, and studies from 1933 to 2021, from basic to translational research, using human and animal ...
Marco Antônio Schlindwein Vaz   +8 more
doaj   +1 more source

Impact of Acute Versus Chronic Unilateral Hearing Loss on Head Movement in a Novel Binaural Task

open access: yesThe Laryngoscope, Volume 136, Issue 1, Page 434-442, January 2026.
Individuals with single‐sided deafness (SSD) may develop adaptive listening strategies with head movement patterns to optimize monaural localization and speech‐in‐noise understanding. Granular understanding of adaptive behaviors may better inform rehabilitation for SSD.
Madison V. Epperson   +4 more
wiley   +1 more source

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

open access: yesAdvanced Science, Volume 12, Issue 41, November 6, 2025.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng   +4 more
wiley   +1 more source

Radiological Configuration of the Vestibular Aqueduct Predicts Bilateral Progression in Meniere's Disease

open access: yesFrontiers in Neurology, 2021
Objective: Meniere's disease (MD) progresses from unilateral to bilateral disease in up to 50% of patients, often chronically and severely impairing balance and hearing functions.
David Bächinger   +6 more
doaj   +1 more source

Bilateral Enlarged Vestibular Aqueduct: Auditory, Genetic and Radiological Characterization, and Benefits of Cochlear Implants

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 5, Page 1215-1227, November 2025.
Abstract Objective The study aimed to describe the auditory phenotype of patients with bilateral enlarged vestibular aqueduct, including benefits of cochlear implantation, and to look for genotype‐phenotype correlation. Study Design Retrospective single‐center study. Setting Tertiary adult reference center.
Augustin Vigouroux   +9 more
wiley   +1 more source

Microsurgical Outcomes in 1000 Patients With Cerebellopontine Angle Tumors: A Comprehensive Cohort Analysis

open access: yesOtolaryngology–Head and Neck Surgery, Volume 173, Issue 5, Page 1236-1244, November 2025.
Abstract Objective To summarize the outcomes of 1000 consecutive microsurgical resection of cerebellopontine angle tumors. Study Design Retrospective cohort study. Setting Single tertiary care institution. Methods We analyzed 1000 patients who underwent microsurgical resection of cerebellopontine angle tumors between November 2017 and August 2024 ...
Joshua Lee   +9 more
wiley   +1 more source

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