Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology
Eye &ENT Research, EarlyView.Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang +9 more
wiley +1 more source
Clinical and genealogical study of patients with endometrial hyperplasia and cancer in Kyiv region
, 1970 L.G. Buchynska +3 more
openalex +1 more source
Detection of p53 Gene Mutations in Human Ovarian and Endometrial Cancers by Polymerase Chain Reaction‐Single Strand Conformation Polymorphism Analysis [PDF]
, 1992 Mariko Fujimoto Naito +7 more
openalex +1 more source
Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
International Journal of Cancer, EarlyView.Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner +3 more
wiley +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, EarlyView.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Endometrial Cancer Trends in England and Wales: A Possible Protective Effect of Oral Contraception [PDF]
, 1990 L Villard, Mike Murphy
openalex +1 more source
Understanding delays in breast cancer diagnosis in Africa: Key insights and contributing factors
International Journal of Cancer, EarlyView.What's New? Despite lower incidence rates, Africa has the highest age‐standardized breast cancer mortality rates globally. Using Bronfenbrenner's ecological model to classify multilevel influences on the individual, this scoping review shows that a lack of knowledge about breast cancer is the primary factor contributing to breast cancer diagnostic ...
Liza A. Hoveling +6 more
wiley +1 more source
Characterization of a 54 kDa, α1Antitrypsin‐like Protein Isolated from Ascitic Fluid of an Endometrial Cancer Patient [PDF]
, 1991 Naotake Tanaka +5 more
openalex +1 more source
International Journal of Cancer, EarlyView.What's New? Cancer, cardiovascular disease, and type 2 diabetes share common lifestyle‐related risk factors. This large‐scale prospective cohort study examined and compared the associations between 13 simple lifestyle scores and these major non‐communicable diseases.
Jie Ding +3 more
wiley +1 more source
The role of UPR‐related long noncoding RNAs in development of endocrine resistance in breast cancer
International Journal of Cancer, EarlyView.Abstract Breast cancer patients who express estrogen receptor α (ER) typically receive endocrine therapy as a first‐line treatment. Most ER‐positive breast cancer patients initially respond to endocrine therapy, but up to 40% of patients develop resistance over time, and the main mechanism is aberrant activation of ER signaling pathways.
Wen Liu, Sahil Gupta, Sanjeev Gupta
wiley +1 more source