Results 151 to 160 of about 238,870 (356)

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Factors associated with Type I and Type II endometrial cancer

, 2010
Ashley S. Felix, Joel L. Weissfeld, Roslyn A. Stone, Robert Bowser, Mamatha Chivukula, Robert P. Edwards, Faina Linkov   +6 more
openalex   +1 more source

212 Multiplex qPCR hotspot testing of pathogenic POLE mutations: a rapid, simple and reliable approach for POLE assessment in endometrial cancer [PDF]

, 2021
AS Van den Heerik, Natalja T. ter Haar, Nanda Horeweg, Tom van Wezel, Carien L. Creutzberg, Vincent T.H.B.M. Smit, Tjalling Bosse   +6 more
openalex   +1 more source

Impacts of Diets and Food Plans in Health and Diseases—A Narrative Review

Food Safety and Health, EarlyView.
This review emphasizes different diet types, providing insights into their nutritional content and health effects. Vegetarian and vegan diets, ketogenic diets, Mediterranean diets, Western diets, pescatarian diets, flexitarian diets, and territorial diversified diets are discussed, highlighting their influences on health, and diseases.
Md. Mahbubar Rahman, Manisha Pandit, Bhawana Thukral, Morshed M. Khandoker   +3 more
wiley   +1 more source

Mechanism of regulation of KIF23 on endometrial cancer cell growth and apoptosis

Discover Oncology
Objective The global incidence of endometrial cancer, a malignant tumor in females, is on the rise. It is one of the most common gynecological cancers. Early-stage endometrial cancers can often be treated successfully with uterine extirpation.
Ruiying Zhuang, Haiyan Liu
doaj   +1 more source

Exploring Transitions in Care Among Patients With Head and Neck Cancer: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Individuals living with and beyond head and neck cancer (HNC) experience many transitions in care (TiC), as their treatment and care involve a team of multidisciplinary healthcare providers across a variety of settings. TiC can be associated with medical error, patient dissatisfaction with care, and overuse of healthcare resources ...
L. Fillo, A. Hezam, J. Kersen, S. Kurbatfinski, A. Thomas, S. Ibadin, D. L. Lorenzetti, S. P. Chandarana, J. C. Dort, K. M. Sauro   +9 more
wiley   +1 more source

Endometrial Cancer: Comparison of Patients with Synchronous Primary Carcinoma of the Endometrium and Ovary vs. Endometrial Carcinoma with Ovarian Metastases [PDF]

, 2012
I Juhasz-Böss, Tanja Fehm, Steffi Becker, Ralf Rothmund, Bernhard Krämer, A Staebler, D. Wallwiener, E.-F. Solomayer   +7 more
openalex   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Reprogramming SREBP1‐dependent lipogenesis and inflammation in high‐risk breast with licochalcone A: A novel path to cancer prevention

International Journal of Cancer, EarlyView.
What's New? Endocrine drugs repurposed from treatment protocols are the primary medications available for breast cancer (BC) prevention in at‐risk women. Adverse effects, however, significantly minimize uptake and prevention impact. Here, the authors investigated licochalcone A (LicA), a non‐endocrine anti‐inflammatory agent with reported hematologic ...
Atieh Hajirahimkhan, Elizabeth T. Bartom, Carolina H. Chung, Xingyu Guo, Kyli Berkley, Seyyedmohsen Hosseinibarkooie, Zahra Assadi, Shao Huan Samuel Weng, Raymond Moellering, Oukseub Lee, Ruohui Chen, Wonhwa Cho, Sriram Chandrasekaran, Susan E. Clare, Seema A. Khan   +14 more
wiley   +1 more source