Results 151 to 160 of about 4,742,503 (345)
What's New? Lynch syndrome is a prevalent cause of hereditary gynecological cancers, but the timeline of molecular alterations preceding malignancy remains unclear. By studying consecutive surveillance specimens for up to 15 years before cancer diagnosis, the authors found that atypical endometrial hyperplasia was indistinguishable from endometrial and
Anni K. Kauppinen+3 more
wiley +1 more source
Cervicovaginal and endometrial smear of ovarial cancer.
Mitsuharu Ohno+8 more
openalex +2 more sources
What's New? Current knowledge of the genetic architecture underlying the development of renal cell carcinoma‐related multiple primary tumours is limited. The authors comprehensively analysed the results of exome/genome sequencing cohorts including 534 patients to better define genotype–phenotype correlations.
Huairen Zhang+6 more
wiley +1 more source
Integrative omics approaches to uncover liquid‐based cancer‐predicting biomarkers in Lynch syndrome
What's New? Lynch syndrome (LS) significantly increases lifetime cancer risk, necessitating innovative approaches for risk stratification. Current risk assessment methods, however, fail to integrate data from different biological systems, which may be influenced by lifestyle factors.
Minta Kärkkäinen+9 more
wiley +1 more source
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng+4 more
wiley +1 more source
Artificial intelligence in the diagnosis and management of gynecologic cancer
Abstract Gynecologic cancers affect over 1.2 million women globally each year. Early diagnosis and effective treatment are essential for improving patient outcomes, yet traditional diagnostic methods often encounter limitations, particularly in low‐resource settings.
Chaiyawut Paiboonborirak+2 more
wiley +1 more source
Moderate Alcohol Consumption and the Risk of Endometrial Cancer
Christine A. Swanson+6 more
openalex +1 more source
Environment, lifestyle, and cancer in women
Abstract Environmental and lifestyle factors significantly contribute to gynecological cancers. The risk of ovarian cancer, one the most lethal gynecological cancer, is associated with obesity, poor dietary habits, and environmental pollutants, exacerbating hormonal imbalances, inflammation, and oxidative stress.
Sara Farina+3 more
wiley +1 more source