Results 151 to 160 of about 4,742,503 (345)

Molecular analysis of the evolutionary history of endometrial and ovarian carcinoma in Lynch syndrome

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Lynch syndrome is a prevalent cause of hereditary gynecological cancers, but the timeline of molecular alterations preceding malignancy remains unclear. By studying consecutive surveillance specimens for up to 15 years before cancer diagnosis, the authors found that atypical endometrial hyperplasia was indistinguishable from endometrial and
Anni K. Kauppinen   +3 more
wiley   +1 more source

Cervicovaginal and endometrial smear of ovarial cancer.

open access: bronze, 1986
Mitsuharu Ohno   +8 more
openalex   +2 more sources

Clinical and genetic features of multiple primary tumours cohorts with a renal cell carcinoma: Implications for molecular genetic investigations

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Current knowledge of the genetic architecture underlying the development of renal cell carcinoma‐related multiple primary tumours is limited. The authors comprehensively analysed the results of exome/genome sequencing cohorts including 534 patients to better define genotype–phenotype correlations.
Huairen Zhang   +6 more
wiley   +1 more source

Integrative omics approaches to uncover liquid‐based cancer‐predicting biomarkers in Lynch syndrome

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Lynch syndrome (LS) significantly increases lifetime cancer risk, necessitating innovative approaches for risk stratification. Current risk assessment methods, however, fail to integrate data from different biological systems, which may be influenced by lifestyle factors.
Minta Kärkkäinen   +9 more
wiley   +1 more source

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng   +4 more
wiley   +1 more source

Artificial intelligence in the diagnosis and management of gynecologic cancer

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Gynecologic cancers affect over 1.2 million women globally each year. Early diagnosis and effective treatment are essential for improving patient outcomes, yet traditional diagnostic methods often encounter limitations, particularly in low‐resource settings.
Chaiyawut Paiboonborirak   +2 more
wiley   +1 more source

Moderate Alcohol Consumption and the Risk of Endometrial Cancer

open access: bronze, 1993
Christine A. Swanson   +6 more
openalex   +1 more source

Environment, lifestyle, and cancer in women

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Environmental and lifestyle factors significantly contribute to gynecological cancers. The risk of ovarian cancer, one the most lethal gynecological cancer, is associated with obesity, poor dietary habits, and environmental pollutants, exacerbating hormonal imbalances, inflammation, and oxidative stress.
Sara Farina   +3 more
wiley   +1 more source

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