Clinical and genealogical study of patients with endometrial hyperplasia and cancer in Kyiv region
, 1970 L.G. Buchynska +3 more
openalex +1 more source
Exploring Transitions in Care Among Patients With Head and Neck Cancer: A Scoping Review
Head &Neck, EarlyView.ABSTRACT Background Individuals living with and beyond head and neck cancer (HNC) experience many transitions in care (TiC), as their treatment and care involve a team of multidisciplinary healthcare providers across a variety of settings. TiC can be associated with medical error, patient dissatisfaction with care, and overuse of healthcare resources ...
L. Fillo +9 more
wiley +1 more source
Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
International Journal of Cancer, EarlyView.Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner +3 more
wiley +1 more source
Evaluation of the reproducibility of the revised 1988 international federation of gynecology and obstetrics grading system of endometrial cancers with special emphasis on nuclear grading [PDF]
, 1991 Anette Lynge Nielsen +2 more
openalex +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
International Journal of Cancer, EarlyView.Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Preoperative whole pelvic external irradiation in stage I endometrial cancer
, 1981 Nick Ritcher +3 more
openalex +1 more source
Family History of Breast, Ovarian and Endometrial Cancer and Risk of Breast Cancer [PDF]
, 1993 Fabio Parazzini +4 more
openalex +1 more source
Integrative omics approaches to uncover liquid‐based cancer‐predicting biomarkers in Lynch syndrome
International Journal of Cancer, EarlyView.What's New? Lynch syndrome (LS) significantly increases lifetime cancer risk, necessitating innovative approaches for risk stratification. Current risk assessment methods, however, fail to integrate data from different biological systems, which may be influenced by lifestyle factors.
Minta Kärkkäinen +9 more
wiley +1 more source
International Journal of Cancer, EarlyView.What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman +15 more
wiley +1 more source