Results 171 to 180 of about 4,877,549 (387)

Detecting FR‐⍺ Expression Level in Cytology Effusion Specimens From Ovarian Cancer and Comparing It With Tissue Specimens

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Folate receptor‐⍺ (FR‐⍺) is an attractive target for targeted therapy. Mirvetuximab soravtansine (MIRV) has been approved by the United States Food and Drug Administration (FDA) for treating adult patients with FR‐⍺ positive, platinum‐resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Therefore,
Yadan Ma, Xiaofei Yu, Xiaohong Duan, Siqian Huang, Sishi Bai, Baizhou Li   +5 more
wiley   +1 more source

The role of myeloid-derived suppressor cells in endometrial cancer displaying systemic inflammatory response: clinical and preclinical investigations

OncoImmunology, 2019
Systemic inflammatory responses including thrombocytosis, leukocytosis, or neutrophilia have gained attention as prognostic indicators in patients with various solid malignancies.current study, we aimed to investigate the clinical implications and ...
Eriko Yokoi, Seiji Mabuchi, Naoko Komura, Kotaro Shimura, Hiromasa Kuroda, Katsumi Kozasa, Ryoko Takahashi, Tomoyuki Sasano, Mahiru Kawano, Yuri Matsumoto, Michiko Kodama, Kae Hashimoto, Kenjiro Sawada, Tadashi Kimura   +13 more
doaj   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

Developmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki, Rinna Kanai, Sayuri Tatsuta, Shinichi Kawaguchi, Masatsune Itoh, Shinsuke Ohba, Makoto Abe   +6 more
wiley   +1 more source

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, EarlyView.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Targeting the splicing factor SNRPB inhibits endometrial cancer progression by retaining the POLD1 intron

Experimental and Molecular Medicine
Dysregulated alternative splicing has been closely linked to the initiation and progression of tumors. Nevertheless, the precise molecular mechanisms through which splicing factors regulate endometrial cancer progression are still not fully understood ...
Yingwei Li, Zhongshao Chen, Huimin Xiao, Yanling Liu, Chen Zhao, Ning Yang, Cunzhong Yuan, Shi Yan, Peng Li   +8 more
doaj   +1 more source

The prognostic role of mitosis index, stage and grade of endometrial cancer in Dr. Soetomo General Academic Hospital Surabaya, Indonesia, in 2018-2020

Majalah Obstetri dan Ginekologi
HIGHLIGHTS 1. Mitotic index and grade are prognostic factors for endometrial cancer, but both are independent. 2. Stage and mitotic index associated with cell proliferation affect the prognosis of endometrial cancer.
Farida Umi Choviva, Willy Sandhika, Pungky Mulawardhana   +2 more
doaj   +1 more source

Opportunities to restore sexual function in reproductive-aged women after treatment for endometrial cancer and borderline ovarian tumors [PDF]

, 2018
А. Е. Солопова, L. E. Idrisova, А Ю Власина, V. Moskvicheva   +3 more
openalex   +1 more source

Canned Foods: Evolution, Benefits, and Health Implications of Modern Packaging

Food Safety and Health, EarlyView.
This graphical abstract presents a concise visual overview of canned food technology, highlighting its historical evolution, key benefits, and associated health risks. It integrates timelines, icons, and summary points to clearly communicate advancements in preservation, consumer advantages, and potential safety concerns in a single schematic ...
Shaswati Rout, Priyadarsini Sahoo, Anuprita Ray, Shuvendu Shekhar Mohapatra   +3 more
wiley   +1 more source

Exploring Transitions in Care Among Patients With Head and Neck Cancer: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Individuals living with and beyond head and neck cancer (HNC) experience many transitions in care (TiC), as their treatment and care involve a team of multidisciplinary healthcare providers across a variety of settings. TiC can be associated with medical error, patient dissatisfaction with care, and overuse of healthcare resources ...
L. Fillo, A. Hezam, J. Kersen, S. Kurbatfinski, A. Thomas, S. Ibadin, D. L. Lorenzetti, S. P. Chandarana, J. C. Dort, K. M. Sauro   +9 more
wiley   +1 more source

Metastatic Cutaneous Adnexal Carcinoma of the Head and Neck With Durable Response to an Aromatase Inhibitor Combined With a Cyclin‐Dependent Kinase 4/6 Inhibitor

Head &Neck, EarlyView.
ABSTRACT Background Cutaneous adnexal carcinomas are a very rare group of cancers arising from appendageal structures of the skin. More than half occur in the head and neck region. No standard treatments exist for metastatic disease. Methods A 48‐year‐old postmenopausal female presented with an enlarging scalp lesion.
Nilesh Kapoor, Manasa Narasimman, Travis Vandergriff, Amy L. Jones   +3 more
wiley   +1 more source