Results 191 to 200 of about 210,312 (353)
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner+7 more
wiley +1 more source
Clinical and genealogical study of patients with endometrial hyperplasia and cancer in Kyiv region
L.G. Buchynska+3 more
openalex +2 more sources
Abstract Increasing evidence links the gut microbiome to carcinogenesis. Disruptions in estrogen regulation by the estrobolome—gut microbiota with estrogen‐related functions—may promote breast cancer. However, precise information on estrobolome targets and their underlying mechanisms is limited. This review identifies relevant targets for measuring the
Ashley H. Larnder+2 more
wiley +1 more source
OBJECTIVE: The present study aims to determine the risk of premenopausal endometrial carcinoma by analyzing c-erb-B2 overexpression in patients with polycystic ovary syndrome (PCOS).
Feyza Arman+7 more
doaj
Evaluation of the reproducibility of the revised 1988 international federation of gynecology and obstetrics grading system of endometrial cancers with special emphasis on nuclear grading [PDF]
Anette Lynge Nielsen+2 more
openalex +1 more source
Prospective evaluation of 92 protein biomarkers for early detection of endometrial cancer
What's New? In this prospective study, the authors evaluated the discrimination capacity of 92 cancer‐related proteins as potential early detection biomarkers for endometrial cancer using blood samples from two large‐scale European population cohorts (EPIC and Janus).
Victoria Cooley+12 more
wiley +1 more source
Background Endometrial cancer is the most common malignancy in women in developed countries, and its incidence is increasing annually. Due to the availability and cost‐effectiveness of serum markers of red cell distribution width (RDW), and mean platelet
Zahra Rafiei Sorouri+3 more
doaj +1 more source
Family History of Breast, Ovarian and Endometrial Cancer and Risk of Breast Cancer [PDF]
Fabio Parazzini+4 more
openalex +1 more source
What's New? While estrogens, obesity, and alcohol are recognized risk factors for breast cancer, a viral hypothesis has been suggested based on the murine model of Mouse Mammary Tumor Virus (MMTV)‐induced mammary tumors. This study analyzed sequences of the human homolog of MMTV across human breast carcinoma histotypes, detecting the virus in all types
Prospero Civita+12 more
wiley +1 more source
Stump pyometra in a spayed female dog secondary to tamoxifen
A 2‐year‐old spayed female dog treated successfully for sclerosing encapsulating peritonitis for 11 months with tamoxifen, cyclosporine, and a short‐term course of prednisone began developing signs of enlarged vulva and discharge. A stump pyometra was confirmed on ultrasound and computed tomography and exploratory laparotomy was performed to remove the
Caryn Ehrhardt+5 more
wiley +1 more source