Results 241 to 250 of about 141,167 (306)

Transumbilical laparoendoscopic single‐site surgery versus conventional multi‐port laparoscopy for myomectomy: A large single‐center retrospective study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
This retrospective observational study compared clinical outcomes from patients who underwent transumbilical laparoendoscopic single‐site surgery (single‐site laparoscopy) or conventional multi‐port laparoscopy for myomectomy. Single‐site laparoscopy and multi‐port laparoscopy showed similar performance in terms of surgical safety.
Xu Yang, Hong Liao, Hongyu Jin, Fan Yang, Sijing Chen, Yu Chen, Jianhong Liu, Xiaorong Qi, Kana Wang, Jinke Li, Qiao Wang, Ying Zheng   +11 more
wiley   +1 more source

Defining low-risk group before surgical treatment in endometrial cancer: A retrospective review. [PDF]

Medicine (Baltimore)
Kaban A, Kinter AK, Öcal EUB, Kasapoğlu A, Kilinç A, Polat T, İlhan Y.   +6 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Impact of <i>IGF2BP2</i> genetic variants and expression levels with the progression of endometrial cancer. [PDF]

Int J Med Sci
Kan CY, Sun YH, Lee CY, Su SC, Chang CC, Tang CH, Chu HJ, Wang PH, Yang SF.   +8 more
europepmc   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

From Epigenetic Dysregulation to Therapeutic Reprogramming in Endometrial Cancer: A State-Response Framework for Treatment Resistance. [PDF]

Int J Mol Sci
Srivastava M, Singh S, Kumar P, Moond N, Chouhan A, Mann K, Kumari S, Banerjee M, Kushwah AS.   +8 more
europepmc   +1 more source

Ketogenic Diet and β‐Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti‐PD‐L1 Immunotherapy Efficacy

Cancer Science, EarlyView.
Ketogenic diet and β‐hydroxybutyrate (β‐HB) suppress bladder cancer growth through direct anti‐tumor mechanisms and enhance anti‐PD‐L1 immunotherapy efficacy. β‐HB upregulates PD‐L1 via JAK2‐STAT3 activation and remodels the tumor immune microenvironment, sensitizing tumors to immune checkpoint blockade. ABSTRACT The limited clinical efficacy of immune
Yuan Zeng, Gangli Gu, Lin Yang, Bohao Fan, Haochen Cui, Lei Yan, Zhao Liu   +6 more
wiley   +1 more source

Redefining the Treatment Landscape of Advanced Endometrial Cancer in the Era of Immunotherapy and Precision Oncology. [PDF]

Cancers (Basel)
Cassaniti M, Morelli I, Boschi AC, Scodes S, Comerci G, Casanova C, Tamberi S.   +6 more
europepmc   +1 more source

ADSC‐Derived CCL8 Regulates HIF‐1α Signaling and Promotes Colorectal Cancer Progression in a 3D Coculture Platform

Cancer Science, EarlyView.
Schematic illustration showing how CRC‐associated ADSC‐derived CCL8 promotes colorectal cancer cell migration through ERK/HIF‐1α signaling in a 3D coculture platform. ABSTRACT This study aimed to recapitulate adipose‐tumor interactions within the colorectal cancer (CRC) tumor microenvironment (TME) and to elucidate the role of adipose‐derived stem ...
Jeong‐Eun Yun, Yeseon Son, Jieun Seo, Ki Yong Hong, Junji Fukuda, Do‐Won Jeong, Jong‐Wan Park, Yang‐Sook Chun   +7 more
wiley   +1 more source

Diabetes, Obesity, and Endometrial Cancer: A Review. [PDF]

Curr Oncol
Hooks O, Jhumkhawala V, Sibson K, Shrontz A, Krishnan SS, Ahmad S.   +5 more
europepmc   +1 more source