Prognostic characteristics and recurrence patterns of grade 1 endometrial carcinoma: a large retrospective analysis of a tertiary center. [PDF]
Sadeghi N +13 more
europepmc +1 more source
Abstract Background Metformin and glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) may reduce the risk of adiposity‐related cancers in patients with type 2 diabetes (T2D). The potential synergistic effects of these treatments on cancer incidence remain unclear, considering their distinct biological mechanisms and their associated effects on body ...
Alex E. Henney +6 more
wiley +1 more source
Intratumoral Collinsella aerofaciens exhibits antitumor activity in endometrial carcinoma through activation of the p53 signaling pathway. [PDF]
Tao M +13 more
europepmc +1 more source
Abstract Recent studies highlight the important roles of cuproptosis in cancer cells. However, the roles of the cuproptosis‐related genes (CRGs) in different cancers are still not fully understood. Comprehensive analysis was performed using open‐source bioinformatic platforms to disclose the expression profiles, prognostic significance, genomic and ...
Xinyu Ge +10 more
wiley +1 more source
Pulmonary tumor thrombotic microangiopathy associated with endometrial carcinoma: A case report. [PDF]
Beppu R +6 more
europepmc +1 more source
Targeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
Abstract Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...
Florian Perner +3 more
wiley +1 more source
Integrated transcriptomic and immunoinformatics analysis identifies tpx2, bub1b, and ube2c as diagnostic biomarkers and therapeutic targets in endometrial carcinoma. [PDF]
Zhou S +7 more
europepmc +1 more source
Therapeutic targeting of chromatin alterations in leukemia and solid tumors
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner +7 more
wiley +1 more source
Construction of prognostic risk prediction model of endometrial carcinoma based on bioinformatics analysis. [PDF]
Zhang Y, Zhou G.
europepmc +1 more source

