Results 251 to 260 of about 131,241 (336)

Mitochondrial Dysfunction in Aging: Future Therapies and Precision Medicine Approaches

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
Mitochondria play a critical role in aging and aging‐related diseases. This review systematically explores the mechanisms underlying mitochondrial deterioration during aging and highlights innovative therapeutic strategies for these mitochondrial problems.
Lanlan Jia   +4 more
wiley   +1 more source

Frameshift mutations at coding mononucleotide repeat microsatellites in endometrial carcinoma with microsatellite instability

open access: bronze, 2000
Lluís Catasús   +6 more
openalex   +1 more source

Targeting Immune Checkpoints: Basic Signaling Pathways and Clinical Translation in Cancer Therapeutics

open access: yesMedComm – Oncology, Volume 4, Issue 3, September 2025.
Immune checkpoints in tumor immunotherapy. Ligand binding to the receptor inhibits immune cell function, promotes tumor cell immune escape, and suppresses the immune response. The pathways of action are VISTA‐IGSF11, TIM‐3‐Ceacam1, CD47‐SIRPα, CTLA‐4‐CD80/CD86, PD‐L1‐PD‐1, MHC‐1‐LILRB, and CD24 ‐ Siglec ‐10. There are also other immune checkpoints such
Han Sun   +10 more
wiley   +1 more source

Type II endometrial cancers with minimal, non-invasive residual disease on final pathology: What should we do next? [PDF]

open access: yes, 2019
Cripe, James C   +8 more
core   +1 more source

The estrobolome: Estrogen‐metabolizing pathways of the gut microbiome and their relation to breast cancer

open access: yesInternational Journal of Cancer, Volume 157, Issue 4, Page 599-613, 15 August 2025.
Abstract Increasing evidence links the gut microbiome to carcinogenesis. Disruptions in estrogen regulation by the estrobolome—gut microbiota with estrogen‐related functions—may promote breast cancer. However, precise information on estrobolome targets and their underlying mechanisms is limited. This review identifies relevant targets for measuring the
Ashley H. Larnder   +2 more
wiley   +1 more source

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