Results 271 to 280 of about 131,241 (336)

Multifactorial construction of low‐grade and high‐grade endometrial cancer recurrence prediction models

International Journal of Gynecology &Obstetrics, Volume 170, Issue 2, Page 816-826, August 2025.
Abstract Objective To analyze independent risk factors for endometrial cancer (EC), a common female cancer globally, and construct individualized prediction models for EC recurrence. Methods The EC patients from the medical record system were divided into low‐grade (n = 392) and high‐grade (n = 183) groups.
Yachai Li, Jia Yan, Yuanmei Deng, Peixuan Wang, Xue Bai, Wei Qin   +5 more
wiley   +1 more source

Diagnostic Value of MRI for Pelvic Lymph Node Extracapsular Invasion in Early-Stage Endometrial Carcinoma. [PDF]

Int J Womens Health
Bao Q, Zheng L, Hong L.
europepmc   +1 more source

A Case of Polymerase Proofreading‐Associated Polyposis: Challenges in Genetic Diagnosis

JGH Open, Volume 9, Issue 8, August 2025.
ABSTRACT Background Polymerase proofreading‐associated polyposis (PPAP) is a rare autosomal dominant hereditary syndrome caused by germline pathogenic variants in the POLE or POLD1 genes. It is clinically similar to familial adenomatous polyposis (FAP) and Lynch syndrome, making diagnosis difficult.
Haruka Ito, Akiko Chino, Arisa Ueki, Keika Kaneko, Shoichi Saito   +4 more
wiley   +1 more source

Immunocytochemical examination of Akt, mTOR, and Pax-2 for endometrial carcinoma through thin-layer endometrial cytology. [PDF]

Front Med (Lausanne)
Ma K, Yang X, Yang Z, Meng Y, Wen J, Chen R, Yang J, Liao Q.   +7 more
europepmc   +1 more source

The Pill and Cancer [PDF]

, 1985
Hume, Kevin
core   +1 more source

PI3K/AKT/mTOR Axis in Cancer: From Pathogenesis to Treatment

MedComm, Volume 6, Issue 8, August 2025.
The PI3K/AKT/mTOR signaling axis is crucial in cancer progression, regulating cell growth, survival, and metabolism. Often hyperactivated through mutations or loss of tumor suppressors such as PTEN, this pathway promotes cancer cell proliferation and survival by inhibiting apoptosis and activating mTOR, which drives protein synthesis and suppresses ...
Mingyang Jiang, Ke Zhang, Zhenwang Zhang, Xinran Zeng, Zihang Huang, Peizhuo Qin, Zhilin Xie, Xue Cai, Milad Ashrafizadeh, Yu Tian, Ruqiong Wei   +10 more
wiley   +1 more source

SIM2, associated with clinicopathologic features, promotes the malignant biological behaviors of endometrial carcinoma cells. [PDF]

BMC Cancer
Nie H, Chen Y.
europepmc   +1 more source

Whole Abdominal Radiotherapy Is Tolerable and Effective in Children and Young Adults With Intra‐Abdominal Sarcoma: A Canadian Sarcoma Research and Clinical Collaboration (CanSaRCC) Study

Pediatric Blood &Cancer, Volume 72, Issue 8, August 2025.
ABSTRACT Background Whole abdominal radiotherapy (WART) is utilized in children, adolescents, and young adults with intra‐abdominal sarcoma, but efficacy and toxicity are uncertain. Methods Sarcoma patients diagnosed at ≤39 years of age between 1998 and 2023 who received WART were identified from a national registry.
Rebecca J. Deyell, Hagit Peretz Soroka, Delaney Sharp, Caroline Ruus, Jeffrey N. Bone, Mai‐Kim Gervais, Audrey Roux, Xiaolan Feng, Natalie Logie, Nicolas Prudhomme, Caroline Holloway, Abha A. Gupta, Derek S. Tsang   +12 more
wiley   +1 more source

FBXL18 promotes endometrial carcinoma progression via destabilizing DUSP16 and thus activating JNK signaling pathway. [PDF]

Cancer Cell Int
Pi J, Wang Y, Zhao Y, Yang J.
europepmc   +1 more source

Peptide‐Drug Conjugates: A New Hope for Cancer

Journal of Peptide Science, Volume 31, Issue 8, August 2025.
Peptide‐drug conjugates (PDCs) are emerging cancer therapeutics inspired by antibody‐drug conjugates, offering targeted delivery via peptide ligands. Despite structural versatility, challenges like instability and rapid clearance hinder clinical progress.
Amy Armstrong, Fleur Coburn, Yanyamba Nsereko, Othman Al Musaimi   +3 more
wiley   +1 more source