Results 181 to 190 of about 93,286 (337)

lncRNA LINC00958 Activates NOTCH3 by Competitively Inhibiting miR‐129‐2‐3p to Exacerbate the Malignant Biological Behaviors of Endometrial Cancer Cells

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Endometrial cancer (EC) is one of the most prevalent gynecologic malignancies, with increasing incidence worldwide. Recent studies have highlighted the critical roles of long noncoding RNAs (lncRNAs) in regulating tumor progression. This study investigated the oncogenic function of lncRNA LINC00958 in EC and its underlying mechanism involving ...
Xia Hong, Su‐Li He
wiley   +1 more source

Genomic landscape of endometrial polyps. [PDF]

Genome Med
Reinikka S, Mehine M, von Nandelstadh P, Ahvenainen T, Khamaiseh S, Nousiainen S, Jokinen V, Pasanen A, Bützow R, Sarvilinna N, Pitkänen E, Vahteristo P.   +11 more
europepmc   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Long Term Disease Control of Brain Metastases From Chemotherapy-Resistant Endometrial Cancer With Lenvatinib and Pembrolizumab: A Case Report. [PDF]

J Obstet Gynaecol Res
Fujioka A, Takahashi A, Amano T, Tanaka Y, Yoneoka Y, Tsuji S.   +5 more
europepmc   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Cytological characteristics of Müllerian adenosarcoma of the uterine corpus: a case report and literature review. [PDF]

J Pathol Transl Med
Kuramoto J, Matsubara C, Sasamoto Y, Tsukada H, Hirose S.   +4 more
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

A Survey of the Reproductive Lesions in Captive Female Non-Human Primates in Italy. [PDF]

Vet Sci
Galietta V, Cocumelli C, Parmigiani R, Bovi E, Palmerini T, Acri C, Di Cerbo P, Aloisi M, Cersini A, Eleni C.   +9 more
europepmc   +1 more source

Type II endometrial cancers with minimal, non-invasive residual disease on final pathology: What should we do next? [PDF]

, 2019
Cripe, James C, Fuh, Katherine C, Litz, Taylor, Lopez, Heather, Mills, Kathryn A, Mutch, David G, Powell, Matthew A, Sun, Lulu, Thaker, Premal H   +8 more
core   +1 more source

Evaluation of Treatment Outcomes of High‐Risk Gestational Trophoblastic Neoplasms (GTNs)

Natural Sciences, EarlyView.
ABSTRACT This study was performed to assess the efficacy, safety, and prognostic factors of treatment protocols in patients with high‐risk gestational trophoblastic neoplasia (GTN). Data of 64 high‐risk GTN patients treated at our clinic between January 1993 and December 2020 were retrospectively analyzed. Patients were classified according to the FIGO
Ayberk Çakır, Fulya Kayıkçıoğlu, Gürkan Özbey, Edis Kahraman   +3 more
wiley   +1 more source